November 27, 2015
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Amyl Nitrite

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Amyl Nitrite

Side Effects


Mild transitory headache, dizziness and flushing of the face are common with the use of amyl nitrite (amyl nitrite inhalant) . The following adverse reactions may occur in susceptible patients: syncope, involuntary passing of urine and feces, hypotension, pallor, cold sweat, tachycardia, restlessness, weakness, vomiting and nausea. Excessively high doses of amyl nitrite (amyl nitrite inhalant) administered chronically may cause methemoglobinemia.

Drug abuse and dependence:

Abuse - Volatile nitrites are abused for sexual stimulation, with headache as a common side effect.

Dependence - Tolerance to nitrites can develop; conditions and duration have not been established.

Read the Amyl Nitrite (amyl nitrite inhalant) Side Effects Center for a complete guide to possible side effects


Taking amyl nitrite (amyl nitrite inhalant) after drinking alcohol may worsen side effects and may cause severe hypotension and cardiovascular collapse.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 9/25/2008

Side Effects

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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