May 27, 2017
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Amyl Nitrite

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Amyl Nitrite

Amyl Nitrite Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 11/20/2015

Amyl Nitrite Inhalant is a fast acting vasodilator used to treat angina pectoris. Amyl nitrite inhalant is available in generic form. Common side effects of Amyl Nitrite include headache, dizziness, flushing of the face, lightheadedness or fainting, involuntary urination or defecation, low blood pressure, nausea, vomiting, shortness of breath, cold sweat, pale skin, rapid heart rate, restlessness, weakness, or slowed breathing.

The recommended dosage of Amyl Nitrite is two to six inhalations of a capsule that is crushed between two fingers. This can be repeated 3 to 5 minutes later if necessary. Alcohol consumption should be avoided because it can interact with Amyl Nitrite. Tell your doctor all medications you use. Sit or lay down when taking Amyl Nitrite. If you are pregnant, only take Amyl Nitrite if clearly needed. Exercise caution if you use Amyl Nitrite and are breastfeeding.

Our Amyl Nitrite Inhalant Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Amyl Nitrite FDA Prescribing Information: Side Effects
(Adverse Reactions)


Mild transitory headache, dizziness and flushing of the face are common with the use of amyl nitrite (amyl nitrite inhalant) . The following adverse reactions may occur in susceptible patients: syncope, involuntary passing of urine and feces, hypotension, pallor, cold sweat, tachycardia, restlessness, weakness, vomiting and nausea. Excessively high doses of amyl nitrite (amyl nitrite inhalant) administered chronically may cause methemoglobinemia.

Drug abuse and dependence:

Abuse - Volatile nitrites are abused for sexual stimulation, with headache as a common side effect.

Dependence - Tolerance to nitrites can develop; conditions and duration have not been established.

Read the entire FDA prescribing information for Amyl Nitrite (Amyl Nitrite Inhalant)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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