October 4, 2015

Analpram HC

Analpram HC®
(hydrocortisone acetate 2.5% pramoxine HCl 1%) Cream 2.5%


Analpram HC® Cream 2.5% is a topical preparation containing hydrocortisone acetate 2.5% w/w and pramoxine hydrochloride 1% w/w in a hydrophilic cream base containing stearic acid, cetyl alcohol, Aquaphor®, isopropyl palmitate, polyoxyl 40 stearate, propylene glycol, potassium sorbate, sorbic acid, triethanolamine lauryl sulfate, and purified water.

Topical corticosteroids are anti-inflammatory and anti-pruritic agents. The structural formula, the chemical name, molecular formula and molecular weight for active ingredients are presented below.

Hydrocortisone acetate Structural Formula Illustration

hydrocortisone acetate Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11, 17-dihydroxy-, (11-beta)- C23H32O6; mol, wt, 404.50

Premoxine hydrochloride Structural Formula Illustration

premoxine hydrochloride 4-(3-(p-butoxyphenoxy)propyl) morpholine hydrochloride C17H27NO3•HCl; mol. Wt:329.87

What are the possible side effects of hydrocortisone pramoxine topical?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • blurred vision, or seeing halos around lights;
  • uneven heartbeats;
  • sleep problems (insomnia);
  • ongoing headache;
  • weight gain, puffiness in your face;
  • increased thirst or urination, weight loss, unusual weakness;
  • fever, sore throat, tired...

Read All Potential Side Effects and See Pictures of Analpram HC »

Last reviewed on RxList: 9/21/2011
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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