May 30, 2017

Analpram HC

Analpram HC Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 01/06/2017

Analpram HC (hydrocortisone acetate 2.5% pramoxine HCl 1%) Cream 2.5% is a topical corticosteroid and anti-itching combination drug used to treat pain, itching, or inflammation of the skin caused by a number of conditions such as allergic reactions, eczema, psoriasis, insect bites, and minor burns or scrapes. Analpram HC is also used on the rectal area to treat itching and inflammation caused by hemorrhoids, anal fissures, or other rectal irritation. Analpram HC is available in generic form. Side effects of Analpram HC include:

  • skin reactions (burning, irritation, dryness, redness, peeling),
  • acne,
  • changes in the color of treated skin,
  • thinning of your skin,
  • blistering skin, or
  • stretch marks.

Analpram HC is supplied in four preparations: 1 oz tube, 4 gm tubes and 1 oz and 4gm Advanced Kits. Analpram HC is generally applied to the affected area as a thin film three to four times daily depending on the severity of the condition. Analpram HC may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Analpram HC; it is unknown if it is harmful to a fetus. It is unknown if Analpram HC topical passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our Analpram HC Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Analpram HC in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • blurred vision, or seeing halos around lights;
  • uneven heartbeats;
  • sleep problems (insomnia);
  • ongoing headache;
  • weight gain, puffiness in your face;
  • increased thirst or urination, weight loss, unusual weakness;
  • fever, sore throat, tired feeling;
  • severe pain, burning, or irritation of treated skin;
  • rectal bleeding;
  • any new redness or swelling where the medicine was applied; or
  • itching, oozing, or other signs of infection.

Less serious side effects may include:

  • mild skin redness, burning, itching, dryness, or peeling;
  • acne;
  • changes in the color of treated skin;
  • thinning of your skin;
  • blistering skin; or
  • stretch marks.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Analpram HC (Hydrocortisone Acetate 2.5% Pramoxine HCl 1%)

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Analpram HC FDA Prescribing Information: Side Effects
(Adverse Reactions)


The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence:

Burning Hypertrichosis Maceration of the skin
Itching Acneiform eruptions Secondary infection
Irritation Hypopigmentation Skin atrophy
Dryness Perioral dermatitis Striae
Folliculitis Allergic contact dermatitis Miliaria

Read the entire FDA prescribing information for Analpram HC (Hydrocortisone Acetate 2.5% Pramoxine HCl 1%)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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