September 1, 2015
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Anaphylaxis (cont.)

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What are anaphylaxis symptoms and signs?

Anaphylaxis is a severe reaction that affects multiple areas of the body.

  • The severity of the reaction varies from person to person.
  • Subsequent reactions to the same trigger are typically similar in nature.
  • The more rapid the onset of symptoms, the more severe the reaction is likely to be.
  • A history of allergic disease (rhinitis, eczema, asthma) does not increase the risk of developing IgE mediated anaphylaxis, but it does incline the person to a non-IgE-mediated reaction.
  • Underlying asthma may result in a more severe reaction and can be more difficult to treat.

The symptoms of an anaphylactic reaction may occur within seconds of exposure or be delayed 15-30 minutes, or even an hour or more after exposure (typical of reactions to aspirin and similar drugs). Early symptoms are often related to the skin and include

  • flushing (warmth and redness of the skin),
  • itching (often in the groin or armpits),
  • hives.

These symptoms are often accompanied by

  • a feeling of "impending doom,"
  • anxiety,
  • sometimes a rapid, irregular pulse.

Frequently following the above symptoms, throat and tongue swelling results in hoarseness, difficulty swallowing, and difficulty breathing.

Symptoms of rhinitis (hay fever) or asthma may occur, causing

  • a runny nose;
  • sneezing, and wheezing, which may worsen the breathing difficulty;
  • vomiting, diarrhea, and stomach cramps may develop.

Some of the time, the mediators flooding the bloodstream cause a generalized opening of capillaries (tiny blood vessels) which results in

These are the typical features of anaphylactic shock.

Medically Reviewed by a Doctor on 6/24/2015

Source: MedicineNet.com
http://www.medicinenet.com/anaphylaxis/article.htm

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