February 13, 2016


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How does Androstenediol work?

Androstenediol is a steroid hormone used by the body to make testosterone and estrogen.

Are there safety concerns?

Androstenediol seems to be unsafe. There is some concern that products can vary from what is listed on the label. Women might experience masculinization, which includes deepening of the voice, facial hair growth, acne, abnormal menstrual periods, male-pattern baldness, thickening of the skin, and depression. Androstenediol might also worsen breast or prostate cancers and other hormone-sensitive cancers. There is also concern that androstenediol might increase the risk for heart disease.

Do not use androstenediol if:
  • You are pregnant or breast-feeding.
  • You have breast cancer.
  • You have a prostate condition known as benign prostate hypertrophy (BPH) or prostate cancer.
  • You have cancer of the uterus or ovaries or other hormone-sensitive cancers.
  • You have a hormone-sensitive condition such as endometriosis or uterine fibroids.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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