Antabuse (Disulfiram) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 24, 2012

Antabuse

Liver Disease »

What is liver disease?

Liver disease is any disturbance of liver function that causes illness. The liver is responsible for many critical functions within the body and should it become diseased or injured, the loss of those functions can cause significant damage to the body. Liver disease is also referred to as hepatic disease.

Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its designated functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.

The liver the largest solid organ in the body; and is also considered a gland because among its many functions, it makes and secretes bile. The liver is located in the upper right portion of the abdomen protected by the rib cage. It has two main lobes that are made up of tiny lobules. The liver cells have two different sources of blood supply. The hepatic ...

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Antabuse Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Prescribing Information

For Patients

Antabuse (disulfiram) is used to treat chronic alcoholism. It is an alcohol antagonist drug. This medication is available in generic form. Common side effects include drowsiness, tiredness, headache, acne, and metallic/garlic-like taste in the mouth as your body gets used to the medication.

In the first phase of treatment, a maximum of 500 mg of Antabuse daily is given in a single dose for one to two weeks. The average maintenance dose of Antabuse is 250 mg daily (range, 125 to 500 mg), not to exceed 500 mg daily. Do not drink alcohol and avoid all alcohol-containing products (e.g., cough and cold syrups, mouthwash, or foods containing alcohol) while taking this medication. Antabuse may interact with isoniazid, monoamine oxidase inhibitors (MAOIs), benzodiazepines, tricyclic antidepressants, warfarin, metronidazole, theophylline, phenytoin, or lithium. Tell your doctor all medications you are taking. During pregnancy, Antabuse should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Our Antabuse (disulfiram) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Antabuse Prescribing Information: Indications & Dosage

ANTABUSE (Disulfiram ) structural formula illustration

Disulfiram is an aid in the management of selected chronic alcohol patients who want to remain in a state of enforced sobriety so that supportive and psychotherapeutic treatment may be applied to best advantage.

Disulfiram is not a cure for alcoholism. When used alone, without proper motivation and supportive therapy, it is unlikely that it will have any substantive effect on the drinking pattern of the chronic alcoholic.

Read the complete drug monograph for Antabuse »

What is Antabuse Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Antabuse Patient Information: Side Effects

Severe and sometimes fatal liver problems have occurred in patients taking disulfiram even without a prior history of liver problems.

If you experience any of the following serious side effects, stop taking disulfiram and seek emergency medical attention:

an allergic reaction (swelling of your lips, tongue, or face; shortness of breath; closing of your throat; or hives);
seizures;
extreme tiredness;
dark urine;
yellowing of the skin or eyes (jaundice);
large appetite changes;
weakness, dizziness...

Read the complete patient information for Antabuse »

What is Antabuse Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Antabuse Consumer Information: Uses

This medication is used along with counseling and support to treat alcoholism. Disulfiram works by blocking the processing of alcohol in the body. This causes you to have a bad reaction when you drink alcohol.

HOW TO USE: See also Precautions section.

Take this medication by mouth with or without food, usually once daily in the morning or as directed by your doctor. If this medication causes drowsiness, take it at bedtime.

Dosage is based on your medical condition and response to therapy. The maximum recommended daily dose is 500 milligrams. ...

Read the complete consumer information for Antabuse »