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May 24, 2012

Antabuse

Liver Disease »

What is liver disease?

Liver disease is any disturbance of liver function that causes illness. The liver is responsible for many critical functions within the body and should it become diseased or injured, the loss of those functions can cause significant damage to the body. Liver disease is also referred to as hepatic disease.

Liver disease is a broad term that covers all the potential problems that may occur to cause the liver to fail to perform its designated functions. Usually, more than 75% or three quarters of liver tissue needs to be affected before decrease in function occurs.

The liver the largest solid organ in the body; and is also considered a gland because among its many functions, it makes and secretes bile. The liver is located in the upper right portion of the abdomen protected by the rib cage. It has two main lobes that are made up of tiny lobules. The liver cells have two different sources of blood supply. The hepatic ...

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Antabuse Patient Information Including Side Effects

Brand Names: Antabuse

Generic Name: disulfiram (Pronunciation: die sul FER am)

What is disulfiram (Antabuse)?

Disulfiram interferes with the metabolism of alcohol resulting in unpleasant effects when alcohol is consumed.

Disulfiram is used to treat chronic alcoholism.

Disulfiram may also be used for purposes other than those listed in this medication guide.

Antabuse 250 mg

octagonal, white, imprinted with ANTABUSE 250, A

Disulfiram 250 mg-SID

round, white, imprinted with SL 331

What are the possible side effects of disulfiram (Antabuse)?

Severe and sometimes fatal liver problems have occurred in patients taking disulfiram even without a prior history of liver problems.

If you experience any of the following serious side effects, stop taking disulfiram and seek emergency medical attention:

an allergic reaction (swelling of your lips, tongue, or face; shortness of breath; closing of your throat; or hives);
seizures;
extreme tiredness;
dark urine;
yellowing of the skin or eyes (jaundice);
large appetite changes;
weakness, dizziness or loss of coordination; or
severe diarrhea or vomiting.

Other, less serious side effects may be more likely to occur. Continue to take disulfiram and talk to your doctor if you experience

skin rash or acne;
mild headaches;
mild drowsiness or tiredness;
impotence;
metallic taste in the mouth; or
swollen or sore tongue.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about disulfiram (Antabuse)?

Do not drink alcohol while taking disulfiram. Flushing, fast heartbeats, nausea, thirst, chest pain, vertigo, and low blood pressure may occur when alcohol is ingested during disulfiram therapy.

Do not take disulfiram for at least 12 hours after drinking alcohol.

Reactions may occur from drinking alcohol for several weeks after you have stopped taking disulfiram.

Be aware of the alcohol content of other common products such as cough and cold medicines, mouth washes, tonics, sauces, vinegars, and other food products. Alcohol in these products can also cause a reaction.

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