August 31, 2015
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Antinuclear Antibody (cont.)

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What other conditions cause ANAs to be produced?

ANAs can be produced in patients with infections (virus or bacteria), lung diseases (primary pulmonary fibrosis, pulmonary hypertension), gastrointestinal diseases (ulcerative colitis, Crohn's disease, primary biliary cirrhosis, alcoholic liver disease), hormonal diseases (Hashimoto's autoimmune thyroiditis, Grave's disease), blood diseases (idiopathic thrombocytopenic purpura, hemolytic anemia), cancers (melanoma, breast, lung, kidney, ovarian and others), skin diseases (psoriasis, pemphigus), as well as in the elderly and those people with a family history of rheumatic diseases.

Can medications cause ANAs to be produced?

Many medications can sometimes stimulate the production of ANAs, including procainamide (Procan SR), hydralazine (Apresoline), and phenytoin (Dilantin). ANAs that are stimulated by medication are referred to as drug-induced ANAs. This does not necessarily mean that any disease is present when these ANAs are "induced." Sometimes diseases are associated with these ANAs, and they are referred to as drug-induced diseases.

Medically Reviewed by a Doctor on 5/7/2015

Source: MedicineNet.com
http://www.medicinenet.com/antinuclear_antibody/article.htm

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