Antiphospholipid Syndrome (cont.)
William C. Shiel Jr., MD, FACP, FACR
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
Kenneth Kaye, MD
Dr. Kaye received a Bachelor of Arts degree with honors from the University of California, San Diego in Applied Mechanics and Engineering Sciences. After graduating from New York Medical College, he completed his internship and residency training in pathology at Harbor - UCLA Medical Center.
In this Article
- Antiphospholipid syndrome facts
- What is antiphospholipid syndrome?
- What laboratory tests can support the diagnosis of antiphospholipid syndrome?
- What causes antiphospholipid syndrome?
- How is antiphospholipid syndrome treated?
- What is catastrophic antiphospholipid syndrome?
- Find a local Rheumatologist in your town
What is catastrophic antiphospholipid syndrome?
Catastrophic antiphospholipid syndrome (CAPS) is a variant of antiphospholipid syndrome that is characterized by blockage of many blood vessels throughout the body. As a result of catastrophic antiphospholipid syndrome, many organs can be affected, including the skin, lungs, brain, heart, kidneys, and bowels. Catastrophic antiphospholipid syndrome is treated with anticoagulation, corticosteroids (cortisone medication), and plasmapheresis (plasma exchange).
Catastrophic antiphospholipid syndrome is rare. Catastrophic antiphospholipid syndrome is sometimes referred to as Asherson's syndrome after the researcher who described it in the early 1990s.
Medically reviewed by David Hoffman, MD; American Board of Internal Medicine with subspecialties in Oncology and Hematology
Bucciarelli S., et al. Mortality in the Catastrophic Antiphospholipid Syndrome. Arthritis & Rheumatism 2006;2568-76.
Kelley's Textbook of Rheumatology, W B Saunders Co, edited by Shaun Ruddy, et al., 2000.
American College of Rheumatology, Annual Scientific Meeting; November, 2006, 2007.
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