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Antizol Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Antizol (fomepizole) is an antidote used to treat poisoning with ethylene glycol (antifreeze) or methanol (contained in solvents, fuels, and other household or automotive chemicals). Antizol is sometimes used together with hemodialysis to rid the body of a poison. Antizol is available in generic form. Common side effects of Antizol include mild skin rash, heartburn, nausea, vomiting, diarrhea, loss of appetite, dizziness, drowsiness, anxiety, headache, metallic taste in mouth, hangover feeling, back pain, sore throat, ringing in ears, or changes in vision, changes in smell or taste senses.
Antizol is administered in a clinical setting and dose is determined by a physician. Antizol may interact with phenytoin, carbamazepine, cimetidine, or ketoconazole. Tell your doctor all medications and supplements you use. Antizol may be harmful to a fetus and is not recommended in pregnant women unless prescribed. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. In a poisoning situation, it may not be possible to tell your caregivers that you are pregnant or breastfeeding before you are treated with Antizol. Make sure any doctor caring for your pregnancy or your baby knows you have received the medication.
Our Antizol (fomepizole) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Antizol in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have any of these serious side effects (some are effects of the poison and not of fomepizole):
- burning, swelling, or skin changes where the medicine was injected;
- urinating less than usual or not at all;
- fast or slow heart rate, feeling like you may pass out; or
- skin rash, bruising, severe tingling, numbness, pain, muscle weakness.
Less serious side effects may include:
- mild skin rash;
- heartburn, nausea, vomiting, diarrhea;
- loss of appetite;
- dizziness, drowsiness, anxiety, or headache;
- metallic taste in your mouth;
- hangover feeling;
- back pain;
- sore throat;
- ringing in your ears; or
- changes in vision, changes in smell or taste senses.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Antizol (Fomepizole)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Antizol FDA Prescribing Information: Side Effects
The most frequent adverse events reported as drug-related or unknown relationship to study drug in the 78 patients and 63 normal volunteers who received Antizol® (fomepizole) Injection were headache (14%), nausea (11%), and dizziness, increased drowsiness, and bad taste/metallic taste (6% each). All other adverse events in this population were reported in approximately 3% or fewer of those receiving Antizol (fomepizole) and were as follows:
Respiratory: Hiccups, pharyngitis
Skin/Appendages: Application site reaction, rash
Special Senses: Abnormal smell, speech/visual disturbances, transient blurred vision, roar in ear
Read the entire FDA prescribing information for Antizol (Fomepizole)
Additional Antizol Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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