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home > drugs a-z list > anturane (sulfinpyrazone) drug center > anturane (sulfinpyrazone) drug - overdosage and contraindications
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Anturane
What is gout? What is hyperuricemia?
Gout is a disease that results from an overload of uric acid in the body. This overload of uric acid leads to the formation of tiny crystals of urate that deposit in tissues of the body, especially the joints. When crystals form in the joints, it causes recurring attacks of joint inflammation (arthritis). Gout is considered a chronic and progressive disease. Chronic gout can also lead to deposits of hard lumps of uric acid in the tissues, particularly in and around the joints and may cause joint destruction, decreased kidney function, and kidney stones (nephrolithiasis).
Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of p...
Anturane
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Please Note: This Brand Name drug is no longer available in the US.(Generic versions may still be available.)
OVERDOSE
Symptoms
Nausea, vomiting, diarrhea, epigastric pain, ataxia, labored respiration, convulsions, coma. Possible symptoms, seen after overdosage with other pyrazolone derivatives: anemia, jaundice, ulceration.
Treatment
No specific antidote. Induce emesis; gastric lavage; supportive treatment (intravenous glucose infusions, analeptics).
CONTRAINDICATIONS
Patients with an active peptic ulcer or symptoms of gastrointestinal inflammation or ulceration should not receive the drug.
The drug is contraindicated in patients with a history or the presence of:
1. Hypersensitivity to phenylbutazone or other pyrazoles
2. Blood dyacrasias
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
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