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Gout is a disease that results from an overload of uric acid in the body. This overload of uric acid leads to the formation of tiny crystals of urate that deposit in tissues of the body, especially the joints. When crystals form in the joints, it causes recurring attacks of joint inflammation (arthritis). Gout is considered a chronic and progressive disease. Chronic gout can also lead to deposits of hard lumps of uric acid in the tissues, particularly in and around the joints and may cause joint destruction, decreased kidney function, and kidney stones (nephrolithiasis).
Gout has the unique distinction of being one of the most frequently recorded medical illnesses throughout history. It is often related to an inherited abnormality in the body's ability to process uric acid. Uric acid is a breakdown product of purines that are part of many foods we eat. An abnormality in handling uric acid can cause attacks of p...
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Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication.
Seek emergency medical attention.
Symptoms of a sulfinpyrazone overdose include nausea, vomiting, diarrhea, stomach pain, poor coordination, difficulty breathing, seizures, and coma. An overdose of sulfinpyrazone can result in death.
Do not take aspirin, salsalate (Disalcid), magnesium salicylate (Magan, Doan's), choline and magnesium salicylate (Trilisate), or other aspirin-like products unless your doctor approves. These products decrease the effects of sulfinpyrazone. Taking one aspirin a day to reduce the risk of a heart attack is usually acceptable.
Follow your doctor's recommendations about diet.
Do not take aspirin, salsalate (Disalcid), magnesium salicylate (Magan, Doan's), choline and magnesium salicylate (Trilisate), or other aspirin-like products unless your doctor approves. These products decrease the effects of sulfinpyrazone. Taking one aspirin a day to reduce the risk of a heart attack is usually acceptable.
The combination of sulfinpyrazone and acetaminophen (in Tylenol and many other products) can be damaging to your liver. Do not take products that contain acetaminophen unless your doctor approves.
Sulfinpyrazone may increase the effects of the following medicines:
You may need lower doses of these drugs.
Sulfinpyrazone may decrease the effects of other medicines:
You may need higher doses of these drugs.
Niacin (Nicolar, Nicobid, others) may decrease the effects of sulfinpyrazone. A dose adjustment may be necessary.
Drugs other than those listed here may also interact with sulfinpyrazone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Your pharmacist has more information about sulfinpyrazone written for health professionals that you may read.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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