"A US Food and Drug Administration (FDA) advisory panel has backed a new biologic for psoriasis, though the panelists recommended strong warnings about the potential for suicide and self-injurious behavior (SIB) with the drug.
ApexiCon E Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
ApexiCon E (diflorasone diacetate cream USP 0.05%) is a topical corticosteroid indicated for the relief of the inflammatory and pruritic (itching) manifestations of corticosteroid-responsive dermatoses. ApexiCon E is available in generic form as diflorasone diacetate. Side effects of ApexiCon E include:
- thinning or softening of your skin
- skin rash or irritation around your mouth
- swollen hair follicles
- changes in color of treated skin
- crusting of treated skin, or
- stretch marks
Each gram of ApexiCon E Cream (diflorasone diacetate cream USP 0.05%) conČtains: 0.5 mg diflorasone diacetatein 30 or 60 gm tubes. ApexiCon E should be applied to the affected areas as a thin film from one to three times daily depending on the severity or resistant nature of the condition. Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions. If an infection develops, the use of occlusive dressings should be discontinued and appropriate antimicrobial therapy initiated. ApexiCon E may interact with other drugs. Tell your doctor all medications and supplements you use. ApexiCon E and other topical corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Nevertheless, caution should be exercised when topical corticosteroids are administered to a nursing woman. Effectiveness and safety of diflorasone diacetate cream in pediatric patients have not been established.
Our ApexiCon E Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
ApexiCon E in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing diflorasone topical through your skin, such as:
- blurred vision, or seeing halos around lights;
- mood changes;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- muscle weakness, feeling tired.
Less serious side effects may include:
- mild skin itching, burning, or dryness;
- thinning or softening of your skin;
- skin rash or irritation around your mouth;
- swollen hair follicles;
- changes in color of treated skin;
- blisters, pimples, or crusting of treated skin; or
- stretch marks.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for ApexiCon E (Diflorasone Diacetate)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
ApexiCon E FDA Prescribing Information: Side Effects
The following local adverse reactions have been reported with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria.
Read the entire FDA prescribing information for ApexiCon E (Diflorasone Diacetate)
Additional ApexiCon E Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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