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Aphrodyne Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 5/20/2016

Aphrodyne (yohimbine) is a sympatholytic and mydriatic drug used to treat impotence in male patients with vascular or diabetic origins and psychogenic origins. Aphrodyne may be available in generic form. Common side effects of Aphrodyne include:

  • nausea
  • vomiting
  • dizziness
  • nervousness
  • restlessness
  • reduced urination
  • elevated blood pressure or heart rate
  • irritability
  • tremors
  • sweating
  • headache, and
  • skin flushing

The dosage of Aphrodyne is 1 caplet (5.4mg) 3 times a day, taken orally. Aphrodyne may interact with other drugs. Tell your doctor all medications and supplements you use. Aphrodyne is not recommended for use in women, and is therefore unlikely to be used during pregnancy or breastfeeding; consult your doctor.

Our Aphrodyne (yohimbine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Aphrodyne FDA Prescribing Information: Side Effects
(Adverse Reactions)


Yohimbine readily penetrates the CNS and produces a complex pattern of responses in lower doses than required to produce peripheral (alpha)-adrenergic blockage. These include anti-diuresis, a general picture of central excitation including elevated blood pressure and heart rate, increased motor activity, irritability and tremor. Sweating, nausea and vomiting are common after parenteral administration of the drug. 1,2 Also dizziness, headache, and skin flushing have been reported. 1,3

Read the entire FDA prescribing information for Aphrodyne (Yohimbine)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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