Aptivus (Tipranavir) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 24, 2012

Aptivus

HIV and AIDS: Antiretroviral Drugs, Treatments and Medications »

Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist

Entry Inhibitors
Entry inhibitors block HIV entry into CD4+ cells.

Fusion inhibitors
The only drug in this class is T-20, which is administered as a twice daily subcutaneous injection. The most common side effect is redness and pain at the site of injection. Rarely, infection can occur at the injection site. There also are reports of generalized allergic reactions.

CCR5 antagonist
Although there were some early concerns of liver inflammation for drugs in this class, MVC appeared to be well tolerated in clinical trials without any specific toxicities attributable to the drug. However, it is a new drug in a new class and the first to actually target the cell. For these reasons, longer follow-up from clinical trials and those followed in the clinic will be very important for assessing the overall safety of the...

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Aptivus Drug Center

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Aptivus Prescribing Information: Indications & Dosage

APTIVUS® (tipranavir) Structural Formula Illustration

APTIVUS, co-administered with ritonavir, is indicated for combination antiretroviral treatment of HIV-1 infected patients who are treatment-experienced and infected with HIV-1 strains resistant to more than one protease inhibitor (PI).

This indication is based on analyses of plasma HIV-1 RNA levels in two controlled studies of APTIVUS/ritonavir of 48 weeks duration in treatment-experienced adults and one open-label 48-week study in pediatric patients age 2 to 18 years. The adult studies were conducted in clinically advanced, 3-class antiretroviral (NRTI, NNRTI, PI) treatmen...

Read the complete drug monograph for Aptivus »

What is Aptivus Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Aptivus Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Some people taking tipranavir and ritonavir have developed life-threatening medical problems including liver damage and bleeding in the brain. If you are taking these two medications, call your doctor at once if you have any of the following side effects:

unusual bleeding (such as a nosebleed or blood in your urine or stools);
sudden headache, confusion, problems with vision, speech, or balance;/...

Read the complete patient information for Aptivus »

What is Aptivus Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Aptivus Consumer Information: Uses

Tipranavir must be used in combination with other medications to help control your HIV infection, thereby improving your ability to fight other infections and improving your quality of life. It also lowers your risk of getting complications of HIV disease (e.g., opportunistic infections, cancer). Tipranavir belongs to a class of drugs known as protease inhibitors. To be effective, tipranavir must be given with another protease inhibitor, ritonavir.

Tipranavir is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (e...

Read the complete consumer information for Aptivus »