"The cystic fibrosis (CF) drug Orkambi (Vertex Pharmaceuticals) has received a green light from the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP).
Orkambi is a fixed-dose oral combination "...
(Generic versions may still be available.)
Metaraminol bitartrate is [R-(R*,S*)]-a-(1-aminoethyl)-3-hydroxybenzenemethanol [R-(R*, R*)]- 2,3-dihydroxybutanedioate (1:1) (salt), which is levorotatory. Its empirical formula is C9H13NO2 C4H6O6 , and its structural formula is:
Injection ARAMINE* (Metaraminol Bitartrate, MADE is a sterile solution. Each mL contains:
equivalent to metaraminol ....................... 10 mg
Water for Injection q.s. ad ..... 1 mL
Methylparaben 0.15%, propylparaben 0.02%, and sodium bisulfite 0.2% added as preservatives.
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
Additional Aramine Information
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