"The US Food and Drug Administration (FDA) is ordering stricter warnings and contraindications for the anemia drug ferumoxytol (Ferumoxytol, AMAG Pharmaceuticals), stating that even with current warnings, there have been 79 anaphylactic r"...
Aranesp overdosage can cause hemoglobin levels above the desired level, which should be managed with discontinuation or reduction of Aranesp dosage and/or with phlebotomy, as clinically indicated [see Pharmacodynamics]. Cases of severe hypertension have been observed following overdose with ESAs [see WARNINGS AND PRECAUTIONS].
Aranesp is contraindicated in patients with:
- Uncontrolled hypertension [see WARNINGS AND PRECAUTIONS].
- Pure red cell aplasia (PRCA) that begins after treatment with Aranesp or other erythropoietin protein drugs [see WARNINGS AND PRECAUTIONS].
- Serious allergic reactions to Aranesp [see WARNINGS AND PRECAUTIONS].
Last reviewed on RxList: 1/27/2014
This monograph has been modified to include the generic and brand name in many instances.
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