"The U.S. Food and Drug Administration approved a risk management program to inform healthcare providers and their patients about the risks of a class of drugs called Erythropoiesis-Stimulating Agents (ESAs). For patients with cancer, the program "...
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Details with Side Effects
Aranesp overdosage can cause hemoglobin levels above the desired level, which should be managed with discontinuation or reduction of Aranesp dosage and/or with phlebotomy, as clinically indicated [see Pharmacodynamics]. Cases of severe hypertension have been observed following overdose with ESAs [see WARNINGS AND PRECAUTIONS].
Aranesp is contraindicated in patients with:
- Uncontrolled hypertension [see WARNINGS AND PRECAUTIONS].
- Pure red cell aplasia (PRCA) that begins after treatment with Aranesp or other erythropoietin protein drugs [see WARNINGS AND PRECAUTIONS].
- Serious allergic reactions to Aranesp [see WARNINGS AND PRECAUTIONS].
Last reviewed on RxList: 1/27/2014
This monograph has been modified to include the generic and brand name in many instances.
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