In this Article

• What is pamidronate (Aredia)?
• What are the possible side effects of pamidronate (Aredia)?
• What is the most important information I should know about pamidronate (Aredia)?
• What should I discuss with my healthcare provider before using pamidronate (Aredia)?
• How is pamidronate given (Aredia)?
• What happens if I miss a dose (Aredia)?
• What happens if I overdose (Aredia)?
• What should I avoid while using pamidronate (Aredia)?
• What other drugs will affect pamidronate (Aredia)?
• Where can I get more information?

What happens if I miss a dose (Aredia)?

Call your doctor for instructions if you miss a dose of pamidronate.

What happens if I overdose (Aredia)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using pamidronate (Aredia)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect pamidronate (Aredia)?

Pamidronate can harm your kidneys. This effect is increased when you also use other medicines harmful to the kidneys. You may need dose adjustments or special tests if you have recently used:

• lithium (Lithobid);
• methotrexate (Rheumatrex, Trexall);
• pain or arthritis medicines such as aspirin (Anacin, Excedrin), acetaminophen (Tylenol), diclofenac (Cataflam, Voltaren), etodolac (Lodine), ibuprofen (Advil, Motrin), indomethacin (Indocin), naproxen (Aleve, Naprosyn), and others;
• medicines used to treat ulcerative colitis, such as mesalamine (Pentasa) or sulfasalazine (Azulfidine);
• medicines used to prevent organ transplant rejection, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) or tacrolimus (Prograf);
• IV antibiotics such as amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), amikacin (Amikin), bacitracin (Baci-IM), capreomycin (Capastat), gentamicin (Garamycin), kanamycin (Kantrex), streptomycin, or vancomycin (Vancocin, Vancoled);
• antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir); or
• cancer medicine such as aldesleukin (Proleukin), carmustine (BiCNU, Gliadel), cisplatin (Platinol), ifosfamide (Ifex), oxaliplatin (Eloxatin), streptozocin (Zanosar), or tretinoin (Vesanoid).

This list is not complete and other drugs may interact with pamidronate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about pamidronate.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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