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Aristospan Injection 20

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Aristospan Injection 20 mg

Aristospan®
(triamcinolone hexacetonide) Injectable Suspension, USP
20 mg/mL PARENTERAL

NOT FOR USE IN NEWBORNS

FOR INTRA-ARTICULAR USE

NOT FOR INTRAVENOUS USE

DRUG DESCRIPTION

A sterile suspension containing 20 mg/mL of micronized triamcinolone hexacetonide in the following inactive ingredients:

Polysorbate 80 NF 0.40% w/v
Sorbitol Solution USP 50.00% w/v
Water for Injection qs ad 100.00% V
Hydrochloric Acid and Sodium Hydroxide, if required, to adjust pH to 4.0-8.0
Preservative: Benzyl Alcohol 0.90% w/v

Chemically triamcinolone hexacetonide USP is 9α-Fluoro-11β,16α, 17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-(3,3-dimethylbutyrate). Molecular weight is 532.65. The structural formula is:

 Aristospan® (Triamcinolone Hexacetonide) Structural Formula Illustration

The hexacetonide ester of the glucocorticoid triamcinolone is relatively insoluble (0.0002% at 25°C in water)

What are the possible side effects of triamcinolone injection?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heart rate;
  • feeling short of breath, even with mild exertion;
  • swelling, rapid weight gain;
  • dangerously high blood pressure (severe headache, buzzing in your ears, anxiety, confusion, chest pain);
  • problems with your vision;
  • eye swelling, redness, discomfort, or drainage (may be...

Read All Potential Side Effects and See Pictures of Aristospan Injection 20 mg »

Last reviewed on RxList: 6/22/2009
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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