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Aristospan Injection 20

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Aristospan Injection 20 mg

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Aristospan®
(triamcinolone hexacetonide) Injectable Suspension, USP
20 mg/mL PARENTERAL

NOT FOR USE IN NEWBORNS

FOR INTRA-ARTICULAR USE

NOT FOR INTRAVENOUS USE

DRUG DESCRIPTION

A sterile suspension containing 20 mg/mL of micronized triamcinolone hexacetonide in the following inactive ingredients:

Polysorbate 80 NF 0.40% w/v
Sorbitol Solution USP 50.00% w/v
Water for Injection qs ad 100.00% V
Hydrochloric Acid and Sodium Hydroxide, if required, to adjust pH to 4.0-8.0
Preservative: Benzyl Alcohol 0.90% w/v

Chemically triamcinolone hexacetonide USP is 9α-Fluoro-11β,16α, 17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with acetone 21-(3,3-dimethylbutyrate). Molecular weight is 532.65. The structural formula is:

 Aristospan® (Triamcinolone Hexacetonide) Structural Formula Illustration

The hexacetonide ester of the glucocorticoid triamcinolone is relatively insoluble (0.0002% at 25°C in water)

Last reviewed on RxList: 6/22/2009
This monograph has been modified to include the generic and brand name in many instances.

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