"The U.S. Food and Drug Administration today approved Imbruvica (ibrutinib) to treat patients with mantle cell lymphoma (MCL), a rare and aggressive type of blood cancer.
MCL is a rare form of non-Hodgkin lymphoma and represents about 6 "...
Advise patients to contact a healthcare professional for any of the following:
- Signs and symptoms of infusion reactions including fever, chills, rash, or breathing problems within 24 hours of infusion [see WARNINGS AND PRECAUTIONS, ADVERSE REACTIONS]
- Symptoms of hepatitis including worsening fatigue or yellow discoloration of skin or eyes [see WARNINGS AND PRECAUTIONS]
- New neurological symptoms such as confusion, dizziness or loss of balance, difficulty talking or walking, or vision problems [see WARNINGS AND PRECAUTIONS]
- Bleeding, easy bruising, petechiae, pallor, worsening weakness, or fatigue [see WARNINGS AND PRECAUTIONS]
- Signs of infections including fever and cough [see WARNINGS AND PRECAUTIONS, ADVERSE REACTIONS]
- Pregnancy-Advise pregnant women of potential fetal B-cell depletion [see Use in Specific Populations]
Advise patients of the need for:
- Monitoring and possible need for treatment if they have a history of hepatitis B infection (based on the blood test) [see WARNINGS AND PRECAUTIONS].
- Periodic monitoring for blood counts [see WARNINGS AND PRECAUTIONS]
- Avoiding vaccination with live viral vaccines [see WARNINGS AND PRECAUTIONS]
Last reviewed on RxList: 1/27/2016
This monograph has been modified to include the generic and brand name in many instances.
Additional Arzerra Information
Arzerra - User Reviews
Arzerra User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.