"The U.S. Food and Drug Administration today approved Gazyva (obinutuzumab) for use in combination with chlorambucil to treat patients with previously untreated chronic lymphocytic leukemia (CLL).
CLL is a blood and bone ma"...
Arzerra Patient Information Including Side Effects
Brand Names: Arzerra
Generic Name: ofatumumab (Pronunciation: OH fa TOO mue mab)
- What is ofatumumab (Arzerra)?
- What are the possible side effects of ofatumumab (Arzerra)?
- What is the most important information I should know about ofatumumab (Arzerra)?
- What should I discuss with my healthcare provider before receiving ofatumumab (Arzerra)?
- How is ofatumumab given (Arzerra)?
- What happens if I miss a dose (Arzerra)?
- What happens if I overdose (Arzerra)?
- What should I avoid while receiving ofatumumab (Arzerra)?
- What other drugs will affect ofatumumab (Arzerra)?
- Where can I get more information?
What is ofatumumab (Arzerra)?
Ofatumumab is a monoclonal antibody that affects the actions of the body's immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage.
Ofatumumab is used in to treat chronic lymphocytic leukemia.
Ofatumumab is usually given after other medications have been tried without successful treatment of symptoms.
Ofatumumab may also be used for other purposes not listed in this medication guide.
What are the possible side effects of ofatumumab (Arzerra)?
Some people receiving a ofatumumab injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, confused, itchy, tingly, or have chest pain, jaw or arm pain, back pain, stomach pain, wheezing, chest tightness, or trouble breathing. These reactions can occur during the injection or within 24 hours afterward..
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- change in your mental state, problems with speech or walking, decreased vision (these symptoms may start gradually and get worse quickly);
- nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- fever, chills, body aches, flu symptoms, mouth and throat ulcers, rapid heart rate, rapid and shallow breathing, fainting;
- easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;
- cough with yellow or green mucus, stabbing chest pain, feeling short of breath;
- confusion, weakness on one side of the body, loss of balance or coordination; or
- severe constipation.
Less serious side effects may include:
- mild nausea, diarrhea;
- swelling in your hands or feet.
- cold symptoms such as stuffy nose, sneezing, sore throat;
- tired feeling; or
- mild skin rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Arzerra (ofatumumab injection) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about ofatumumab (Arzerra)?
Ofatumumab increases the risk of a serious viral infection of the brain that can lead to disability or death. This risk is higher if you have a weak immune system or are receiving certain medicines. Call your doctor right away if you have symptoms such as change in your mental state, problems with speech or walking, or decreased vision. These symptoms may start gradually and get worse quickly.
Before you receive ofatumumab, tell your doctor if you have hepatitis or severe COPD.
To be sure this medication is not causing harmful effects, your blood cells, kidney function, and liver function may need to be tested for several months, even after you stop using ofatumumab. Do not miss any follow-up visits to your doctor.
Call your doctor at once if you develop any symptoms of liver damage, such as nausea, stomach pain, loss of appetite, itching, dark urine, clay-colored stools, or jaundice (yellowing of your skin or eyes).
You should also call your doctor right away if you develop any signs of infection such as fever, chills, body aches, flu symptoms, mouth and throat ulcers, easy bruising or bleeding, or cough with mucus and stabbing chest pain.
Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection. Do not receive a "live" vaccine while you are being treated with ofatumumab.
Additional Arzerra Information
- Arzerra Drug Interactions Center: ofatumumab iv
- Arzerra Side Effects Center
- Arzerra Overview including Precautions
- Arzerra FDA Approved Prescribing Information including Dosage
Arzerra - User Reviews
Arzerra User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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