(polidocanol) Injection, for Intravenous use
Asclera (polidocanol injection) is a sterile, nonpyrogenic, and colorless to faintly greenish-yellow solution of polidocanol for intravenous use as a sclerosing agent.
The active ingredient, polidocanol is a non-ionic detergent, consisting of two components, a polar hydrophilic (dodecyl alcohol) and an apolar hydrophobic (polyethylene oxide) chain. Polidocanol has the following structural formula:
C12H25(OCH2CH2)nOH Polyethylene glycol monododecyl ether
Mean extent of polymerization (n) : Approximately 9
Mean molecular weight : Approximately 600
Each mL contains 5 mg (0.5%) or 10 mg (1.0%) polidocanol in water for injection with 5% (v/v) ethanol at pH 6.5-8.0; disodium hydrogen phosphate dihydrate, potassium dihydrogen phosphate are added for pH adjustment.
What are the possible side effects of laureth-9 (Asclera)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; sneezing, runny nose, difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have a serious side effect such as:
- severe pain, burning, or other irritation in your leg;
- discoloration or skin changes where an injection was given;
- sudden severe headache, confusion, problems with vision, speech, or balance;
- severe numbness that does not go away;
- pain, swelling, warmth, or redness in one or both...
Last reviewed on RxList: 4/16/2010
This monograph has been modified to include the generic and brand name in many instances.
Additional Asclera Information
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