Asthma Overview (cont.)
Syed Shahzad Mustafa, MD
After growing up in the Rochester area, Dr. Mustafa pursued his undergraduate studies at the Johns Hopkins University in Baltimore and attended medical school at SUNY Buffalo. He then completed his internal medicine training at the University of Colorado and stayed in Denver to complete his fellowship training in allergy and clinical immunology at the University of Colorado, National Jewish Health, and Children's Hospital of Denver.
Allison Ramsey, MD
Dr. Allison Ramsey earned her undergraduate degree at Colgate University and her medical degree at the University of Rochester School of Medicine and Dentistry. She completed her internal medicine training at the University of Rochester School of Medicine and Dentistry and remained at the university to complete her fellowship training in allergy and clinical immunology. Dr. Ramsey is board certified in internal medicine and allergy and immunology. Her professional interests include the treatment of drug allergy and eosinophilic disorders. She also enjoys teaching medical trainees. She is a member of the American Academy of Allergy, Asthma, and Immunology, the American College of Allergy, Asthma, and Immunology, the New York State Allergy Society, and the Finger Lakes Allergy Society. In her personal life, her interests include exercise, especially running and horseback riding; and spending time with her husband and two children.
William C. Shiel Jr., MD, FACP, FACR
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
In this Article
- What is the definition of asthma?
- Asthma vs. COPD
- What are risk factors and causes of asthma?
- What are the different types of asthma?
- What are asthma symptoms and signs?
- How is asthma diagnosed?
- What are asthma treatment options? Are there home remedies for asthma?
- What should someone do when experiencing an asthma attack?
- What is an asthma action plan?
- What is the prognosis for asthma?
- Is it possible to prevent asthma?
- Asthma FAQs
- Find a local Asthma & Allergy Specialist in your town
How is asthma diagnosed?
The diagnosis of asthma begins with a detailed history and physical examination. Primary-care providers are familiar with the diagnosis of asthma, but specialists such as allergists or pulmonologists may be involved. A typical history is an individual with a family history of allergic conditions or a personal history of allergic rhinitis who experiences coughing, wheezing, and difficulty breathing, especially with exercise or during the night. There may also be a propensity toward bronchitis or respiratory infections. In addition to a typical history, improvement with a trial of appropriate medications is very suggestive of asthma.
In addition to the history and exam, the following are diagnostic procedures that can be used to help with the diagnosis of asthma:
- Lung function testing with spirometry: This test measures lung function as the patient breathes into a tube. If lung function improves significantly following the administration of a bronchodilator, such as albuterol, this essentially confirms the diagnosis of asthma. It is important to note, however, that normal lung function testing does not rule out the possibility of asthma.
- Measurement of exhaled nitric oxide (FeNO): This can be performed by a quick and relatively simple breathing maneuver, similar to spirometry. Elevated levels of exhaled nitric oxide are suggestive of "allergic" inflammation seen in conditions such as asthma.
- Skin testing for common aeroallergens: The presence of sensitivities to environmental allergies increases the likelihood of asthma. Of note, skin testing is generally more useful than blood work (in vitro testing) for environmental allergies. Testing for food allergies is not indicated in the diagnosis of asthma.
- Other potential but less commonly used tests include provocation testing such as a methacholine challenge, which tests for airway hyperresponsiveness. Hyperresponsiveness is the tendency of the breathing tubes to constrict or narrow in response to irritants. A negative methacholine challenge makes asthma much less likely. Specialists sometimes also measure sputum eosinophils, another marker for "allergic" inflammation seen in asthma. Chest imaging may show hyperinflation, but is often normal in asthma. Tests to rule out other conditions, such as cardiac testing, may also be indicated in certain cases.
- Blood testing can sometimes help differentiate between different types of asthma. Helpful blood tests include checking for the level of allergic antibody (IgE) or specialized white blood cells called eosinophils, which are often associated with allergic or extrinsic asthma.
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