Healthy Heart Resources
Featured Centers
- Eating Out? Cut Calories, Heartburn
- 5 Good Ways to Save Money on Medicine
- 8 Ways to Treat Your Allergies
The class of drugs called angiotensin converting enzyme (ACE) inhibitors, as the class name suggests, reduces the activity of angiotensin converting enzyme. ACE converts angiotensin I produced by the body to angiotensin II in the blood. Angiotensin II is a very potent chemical that causes the muscles surrounding blood vessels to contract and narrow the blood vessels. Narrowing of blood vessels increases the pressure within the blood vessels and may lead to high blood pressure (hypertension).
By reducing the activity of ACE, ACE inhibitors decrease the formation of angiotensin II which leads to widening (dilation) of blood vessels, and thereby reduces blood pressure. By lowering blood pressure against which the heart must pump, the amount of work that the heart must do is reduced. ACE inhibitors also reduce blood pressure in the kidneys, slowing the progression of kidney disease due to high blood p...
|
|
Candesartan is in a group of drugs called angiotensin II receptor antagonists. Candesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Candesartan is used to treat high blood pressure (hypertension). It is sometimes given together with other blood pressure medications.
Candesartan is also used to treat kidney problems caused by type 2 (not insulin-dependent) diabetes.
Candesartan may also be used for other purposes not listed in this medication guide.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
In rare cases, candesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.
Call your doctor at once if you have any other serious side effect, such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Do not use this medication without telling your doctor if you are pregnant. Candesartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.
You should not use this medication if you are allergic to candesartan.
Avoid drinking alcohol. It can lower your blood pressure and may increase some of the side effects of candesartan.
Do not use potassium supplements or salt substitutes while you are taking candesartan, unless your doctor has told you to.
To be sure this medication is helping your condition, your blood pressure will need to be checked on a regular basis. Do not miss any scheduled appointments.
Keep using this medication even if you feel fine. High blood pressure often has no symptoms.
In rare cases, candesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.