April 29, 2017
Recommended Topic Related To:


"Today, the U.S. Food and Drug Administration cleared the use of the XSTAT 30 wound dressing, an expandable, multi-sponge dressing used to control severe, life-threatening bleeding from wounds in areas that a tourniquet cannot be placed (such as t"...




Self-Aid and Caregiver Aid Directions for Use.


Step 1 USE THE CORRECT DOSE Adults and children weighing over 90 lbs
(generally over 10 years of age)
2 mg AtroPen® (atropine)
Children weighing 40 lbs to 90 lbs
(generally 4 to 10 years of age)
1 mg AtroPen® (atropine)
Children weighing 15 lbs to 40 lbs
(generally 6 months to 4 years of age) 0.5 mg AtroPen® (atropine)
NOTE: Children weighing under 15 lbs (generally younger than 6 months old) should ordinarily not be treated with the AtroPen® auto-injector. Atropine doses in this age group should be individualized at doses of 0.05 mg/kg.
In an environment where nerve agent (or nerve gas) or insecticide exposure is known or
suspected, the following are mild and severe symptoms of nerve agent intoxication.
You may not have all of these symptoms:
MILD symptoms
  •  Blurred vision and sore eyes
  •  Teary eyes
  •  Runny nose
  •  Increased salivation such as sudden drooling
  •  Chest tightness or difficulty breathing
  •  Tremors throughout the body or muscular twitching
  •  Nausea and vomiting
  •  Involuntary secretions (phlegm from your lungs/airway)

SEVERE symptoms

  •  Strange or confused behavior
  •  Severe difficulty breathing or severe secretions from your lungs/airway
  •  Severe muscular twitching and general weakness
  •  Involuntary urination and defecation (feces)
  •  Convulsions
  •  Unconsciousness
Step 3 TREATMENT OF MILD SYMPTOMS FIRST DOSE: Give one (1) AtroPen® (atropine) if you experience two or more MILD symptoms of nerve gas or insecticide exposure. Look for a helper and have them check you for continued or worsening symptoms. Get medical attention immediately.
ADDITIONAL DOSES: Two (2) additional AtroPen® (atropine) injections given in rapid succession are recommended 10 minutes after receiving the first AtroPen® (atropine) injection if the victim develops any of the SEVERE symptoms listed above. If possible, a person other than the victim should administer the second and third AtroPen® (atropine) injections.
TREATMENT OF SEVERE SYMPTOMS If a victim is encountered who is either unconscious or has any of the SEVERE symptoms listed above, immediately administer three (3) AtroPen® (atropine) injections into the victim's mid-lateral thigh in rapid succession using the appropriate weight-based AtroPen® (atropine) dose.
WARNING: Giving additional AtroPen (atropine) 0 injections by mistake in the absence of nerve agent or insecticide poisoning may cause an overdose of atropine which might result in temporary incapacitation (inability to see clearly or walk properly for several or more hours). Patients with cardiac disease may be at risk for serious adverse events, including death.

Step 4
(A) Snap the grooved end of the plastic sleeve down and over the yellow safety cap. Remove the AtroPen® (atropine) from the plastic sleeve.
Caution: Do not place fingers on green tip.
(B) Firmly grasp the AtroPen® with the green tip pointed down.
(C) Pull off the yellow safety cap with your other hand.
(D) Aim and firmly jab the green tip straight down (a 90° angle) against the outer thigh. The AtroPen® (atropine) device will activate and deliver the medicine when you do this. It is okay to inject through clothing but make sure pockets at the injection site are empty.
Very thin people and small children should also be injected in the thigh, but before giving the AtroPen® (atropine) , bunch up the thigh to provide a thicker area for injection.
(E) Hold the auto-injector firmly in place for at least 10 seconds to allow the injection to finish.
(F) Remove the AtroPen® and massage the injection site for several seconds. If the needle is not visible, check to be sure the yellow safety cap has been removed, and repeat steps C and E, but press harder.
(G) After use, using a hard surface, bend the needle back against the AtroPen® (atropine) and either pin the used AtroPen® (atropine) to the victim's clothing or show the used AtroPen® (atropine) auto-injectors to the first medical person you see. This will allow medical personnel to see the number and dose of AtroPen® (atropine) autoinjectors administered. Move yourself and the exposed individual away from the contaminated area right away.
Try to find medical help.

Last reviewed on RxList: 11/20/2008
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Women's Health

Find out what women really need.