Atrovent Nasal Spray (Ipratropium Bromide Nasal Spray) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Atrovent Nasal Spray

Allergy Drugs: Prescription and OTC »

Allergy medications overview

The arsenal of allergy drugs includes dozens of medications that relieve allergy symptoms when confronted with a trigger known as an allergen. That trigger could be something from a plant, such as pollen, or something from an animal (pet dander, dust mites, cockroaches). Other allergy triggers include certain fragrances or chemical substances.

What causes a person's allergic reaction is highly individual. But the reactions are often universal: swelling and inflammation, especially around the eyes, nose, and throat, usually accompanied by itching.

Some allergy medications work against the effects of histamines, which are released during an allergic reaction. Other medications reduce swelling, affect the immune system, or affect release of other substances associated with allergic reactions.

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Atrovent Nasal Spray User Reviews >>

Atrovent Nasal Spray

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Atrovent®
(ipratropium bromide) Nasal Spray 0.03%

DRUG DESCRIPTION

The active ingredient in ATROVENT® Nasal Spray is ipratropium bromide monohydrate. It is an anticholinergic agent chemically described as 8-azoni-abicyclo (3.2.1) octane,3-(3-hydroxy-1-oxo-2-phenyl-propoxy)-8-methyl-8-(1-methylethyl)-, bromide, monohydrate (endo,syn)-, (±)- :a synthetic quaternary ammonium compound, chemically related to atropine. Its structural formula is:

Atrovent (ipratropium bromide) structural formula illustration

Ipratropium bromide is a white to off-white, crystalline substance. It is freely soluble in lower alcohols and water, existing in an ionized state in aqueous solutions, and relatively in soluble in non-polar media.

ATROVENT (ipratropium bromide) Nasal Spray 0.03% is a metered-dose, manual pump spray unit which delivers 21 mcg(70µL) ipratropium bromide per spray on an anhydrous basis in an isotonic, aqueous solution with pH adjusted to 4.7. It also contains benzalkonium chloride, edetate disodium, sodium chloride, sodium hydroxide, hydrochloric acid, and purified water. Each bottle contains 345 sprays.

What are the possible side effects of ipratropium nasal (Atrovent Nasal)?

Stop using ipratropium nasal and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a fast, pounding heartbeat.

Less serious side effects may include:

headache;
dry nose;
nosebleeds; or
blurred vision.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or...

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What are the precautions when taking ipratropium bromide nasal spray (Atrovent Nasal Spray)?

Before using ipratropium, tell your doctor or pharmacist if you are allergic to it; or to atropine or other belladonna-type drugs; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: glaucoma (narrow-angle), difficulty urinating (for example, due to enlarged prostate).

Although unlikely, this drug may make you dizzy or cause blurred vision or other vision changes. Do not drive, use machinery, or do any activity that requires alertness or clear vision until you are sure you can perform such activities safely. Limit alcoholic beverages.

Before...

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Last reviewed on RxList: 12/5/2008
This monograph has been modified to include the generic and brand name in many instances.