"The U.S. Food and Drug Administration yesterday approved Obizur [Antihemophilic Factor (Recombinant), Porcine Sequence] for the treatment of bleeding episodes in adults with acquired hemophilia A (acquired Factor VIII [FVII] deficiency).
Autoplex-T Patient Information including How Should I Take
In this Article
- What is anti-inhibitor coagulant complex (Autoplex-T)?
- What are the possible side effects of anti-inhibitor coagulant complex (Autoplex-T)?
- What is the most important information I should know about anti-inhibitor coagulant complex (Autoplex-T)?
- What should I discuss with my healthcare provider before using anti-inhibitor coagulant complex (Autoplex-T)?
- How should I use anti-inhibitor coagulant complex (Autoplex-T)?
- What happens if I miss a dose (Autoplex-T)?
- What happens if I overdose (Autoplex-T)?
- What should I avoid while using anti-inhibitor coagulant complex (Autoplex-T)?
- What other drugs will affect anti-inhibitor coagulant complex (Autoplex-T)?
- Where can I get more information?
What should I discuss with my healthcare provider before using anti-inhibitor coagulant complex (Autoplex-T)?
You should not use anti-inhibitor coagulant complex if you are allergic to it.
To make sure you can safely use anti-inhibitor coagulant complex, tell your doctor if you have any of these other conditions:
- coronary artery disease; or
- history of heart attack, stroke, or blood clot.
FDA pregnancy category C. It is not known whether anti-inhibitor coagulant complex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.
It is not known whether anti-inhibitor coagulant complex passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Anti-inhibitor coagulant complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
How should I use anti-inhibitor coagulant complex (Autoplex-T)?
Anti-inhibitor coagulant complex is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Anti-inhibitor coagulant complex is usually given once every 6 to 12 hours until your condition improves.
Anti-inhibitor coagulant complex is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.
Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any medical care provider who treats you should know that you have a bleeding or blood clotting disorder.
Store anti-inhibitor coagulant complex in a refrigerator. Do not freeze. Take the vial out of the refrigerator and allow it to reach room temperature before mixing with the diluent. Do not heat the medicine.
You may store this medicine at room temperature for up to 6 months or until the expiration date on the label.
After mixing anti-inhibitor coagulant complex with the diluent, store the mixture at room temperature and use it within 3 hours. Do not refrigerate mixed medicine.
Additional Autoplex-T Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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