"The U.S. Food and Drug Administration yesterday approved Rixubis [Coagulation Factor IX (Recombinant)] for use in people with hemophilia B who are 16 years of age and older. Rixubis is indicated for the control and prevention of bleeding episodes"...
- Clinician Information:
Autoplex-T Patient Information Including Side Effects
Brand Names: Autoplex T, Feiba NF, Feiba VH Immuno
Generic Name: anti-inhibitor coagulant complex (Pronunciation: an TEE in HIB i tor koe AG yoo lant KOM plex)
- What is anti-inhibitor coagulant complex (Autoplex-T)?
- What are the possible side effects of anti-inhibitor coagulant complex (Autoplex-T)?
- What is the most important information I should know about anti-inhibitor coagulant complex (Autoplex-T)?
- What should I discuss with my healthcare provider before using anti-inhibitor coagulant complex (Autoplex-T)?
- How should I use anti-inhibitor coagulant complex (Autoplex-T)?
- What happens if I miss a dose (Autoplex-T)?
- What happens if I overdose (Autoplex-T)?
- What should I avoid while using anti-inhibitor coagulant complex (Autoplex-T)?
- What other drugs will affect anti-inhibitor coagulant complex (Autoplex-T)?
- Where can I get more information?
What is anti-inhibitor coagulant complex (Autoplex-T)?
Anti-inhibitor coagulant complex is made from proteins normally found in human blood that allow the blood to clot.
Anti-inhibitor coagulant complex is used to treat or prevent bleeding in people with hemophilia A or B and Factor VIII inhibitors.
Anti-inhibitor coagulant complex may also be used for purposes not listed in this medication guide.
What are the possible side effects of anti-inhibitor coagulant complex (Autoplex-T)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), feeling like you might pass out;
- fever, chills, runny nose, and drowsiness, followed by rash and joint pain about 2 weeks later;
- sudden numbness or weakness, especially on one side of the body;
- sudden severe headache, confusion, problems with vision, speech, or balance;
- pain, swelling, warmth, or redness in one or both legs;
- chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
- fast or slow heart rate, weak pulse, trouble breathing, chest pain or cough; or
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- pain around the IV needle or
- numbness or tingling, especially in your face.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Autoplex-T (anti-inhibitor coagulant complex, heat treated) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about anti-inhibitor coagulant complex (Autoplex-T)?
You should not use anti-inhibitor coagulant complex if you are allergic to it.
Before using this medication, tell your doctor if you have coronary artery disease or a history of heart attack, stroke, or blood clot.
Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.
Anti-inhibitor coagulant complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.
Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any medical care provider who treats you should know that you have a bleeding or blood clotting disorder.
Additional Autoplex-T Information
- Autoplex-T Drug Interactions Center: anti-inhibitor coagulant cmplx iv
- Autoplex-T Side Effects Center
- Autoplex-T FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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