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Diabetes mellitus is a condition in which the body does not produce enough insulin or the insulin that is produced is ineffective. Insulin is produced and secreted by the pancreas and is needed for the proper storage and utilization of nutrients (glucose, proteins, and fat) by the cells of the body. Insulin allows nutrients to enter the cells of the body. For example, insulin allows cells to remove glucose from the blood, and the glucose is used to generate the energy that is necessary to fuel the activities of the cells. When insulin is absent or ineffective and the cells receive inadequate amounts of glucose, the body releases more glucose into the blood in an attempt to overcome the block to glucose entering the cells. The additional glucose cannot penetrate the cells, of course, and the glucose levels in the blood rise. High levels of blood and urine glucose is what causes the symptoms and signs of diabetes. For more, please re...
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Medical Editor: John P. Cunha, DO, FACOEP
Avandia (rosiglitazone maleate) is an oral diabetes medicine that helps control blood sugar levels. It is for people with type 2 (non-insulin-dependent) diabetes. Avandia is sometimes used in combination with insulin or other medications, but it is not for treating type 1 diabetes. Avandia is not recommended for use with insulin. Common side effects include headache or cough.
Avandia is administered at a starting dose of 4 mg either as a single daily dose or in 2 divided doses. The dose may be increased by a physician to 8 mg daily in patients who did not respond to lower doses. Drugs that can raise blood sugar such as isoniazid, diuretics (water pills), steroids, phenothiazines, thyroid medicine, birth control pills and other hormones, seizure medicines, and diet pills or medicines to treat asthma, colds or allergies can lead to hyperglycemia (high blood sugar) when taken with Avandia. Drugs that lower blood sugar such as non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), beta-blockers, or probenecid may lead to hypoglycemia (low blood sugar) when taken with Avandia. Other medications that may interfere with Avandia include gemfibrozil, rifampin, and nitrate drugs for chest pain or heart problems. Tell your doctor all medications you are taking. Avandia should be used only when prescribed during pregnancy. It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Our Avandia (rosiglitazone maleate) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
After consultation with a healthcare professional who has considered and advised the patient of the risks and benefits of AVANDIA®, this drug is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus who either are:
Read the complete drug monograph for Avandia »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Patient information?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using rosiglitazone and call your doctor at once if you have any of these serious side effects:
Read the complete patient information for Avandia »
Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
Read the complete consumer information for Avandia »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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