July 26, 2016
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Advise patients:

  • To undergo routine blood pressure monitoring and to contact their health care provider if blood pressure is elevated.
  • To immediately contact their health care provider for unusual bleeding, high fever, rigors, sudden onset of worsening neurological function, or persistent or severe abdominal pain, severe constipation, or vomiting.
  • Of increased risk of wound healing complications during and following Avastin.
  • Of increased risk of an arterial thromboembolic event.
  • Of the increased risk for ovarian failure following Avastin treatment.

Embryo-fetal Toxicity

  • Advise female patients that Avastin may cause fetal harm and to inform their healthcare provider with a known or suspected pregnancy. [See WARNINGS AND PRECAUTIONS, Use In Specific Populations]
  • Advise females of reproductive potential to use effective contraception during treatment with Avastin and for 6 months after the last dose of Avastin. [See Use In Specific Populations]


Last reviewed on RxList: 12/10/2015
This monograph has been modified to include the generic and brand name in many instances.

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