"The US Food and Drug Administration (FDA) has approved an extended-release (ER) morphine sulfate C-II (Arymo ER, Egalet Corp) for the management of pain severe enough to require round-the-clock, long-term opioid management for which alte"...
Avinza Patient Information including How Should I Take
In this Article
- What is morphine (Avinza)?
- What are the possible side effects of morphine (Avinza)?
- What is the most important information I should know about morphine (Avinza)?
- What should I discuss with my healthcare provider before using morphine (Avinza)?
- How should I use morphine (Avinza)?
- What happens if I miss a dose (Avinza)?
- What happens if I overdose (Avinza)?
- What should I avoid while using morphine (Avinza)?
- What other drugs will affect morphine (Avinza)?
- Where can I get more information?
What should I discuss with my healthcare provider before using morphine (Avinza)?
Do not use this medicine if you have ever had an allergic reaction to a narcotic medicine (examples include methadone, morphine, Oxycontin, Darvocet, Percocet, Vicodin, Lortab, and many others), or to a narcotic cough medicine that contains codeine, hydrocodone, or dihydrocodeine.
You should also not take morphine if you are having an asthma attack, or if you have a bowel obstruction called paralytic ileus.
Do not use morphine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.
To make sure you can safely take morphine, tell your doctor if you have any of these other conditions:
- a blockage in your digestive tract (stomach or intestines);
- asthma, COPD, sleep apnea, or other breathing disorders;
- liver or kidney disease;
- underactive thyroid;
- curvature of the spine;
- a history of head injury or brain tumor;
- epilepsy or other seizure disorder;
- low blood pressure;
- gallbladder disease;
- Addison's disease or other adrenal gland disorders;
- enlarged prostate, urination problems;
- mental illness; or
- a history of drug or alcohol addiction.
Morphine may be habit forming and should be used only by the person for whom it was prescribed. Never share morphine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
You may not be able to take morphine unless you are already being treated with a similar opioid pain medicine and your body is tolerant to it. Talk with your doctor if you are not sure you are opioid-tolerant.
FDA pregnancy category C. It is not known whether morphine will harm an unborn baby. Morphine may cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using morphine.
Morphine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Older adults and those who are ill or debilitated may be more likely to have serious side effects.
How should I use morphine (Avinza)?
Take exactly as prescribed. Never take morphine in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It will release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.
To make swallowing easier, you may open the extended-release capsule and sprinkle the medicine into a spoonful of applesauce. Swallow this mixture right away without chewing. Do not save the mixture for later use. Discard the empty capsule.
Measure liquid medicine with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not stop using morphine suddenly, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. You may need to use less and less before you stop the medication completely.
Store at room temperature, away from heat, moisture, and light.
Keep track of the amount of medicine used from each new bottle. Morphine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Always check your bottle to make sure you have received the correct pills (same brand and type) of medicine prescribed by your doctor. Ask the pharmacist if you have any questions about the medicine you receive at the pharmacy.
After you have stopped using this medication, flush any unused pills down the toilet. Throw away any unused liquid morphine that is older than 90 days.
Additional Avinza Information
- Avinza Drug Interactions Center: morphine oral
- Avinza Side Effects Center
- Avinza Overview including Precautions
- Avinza FDA Approved Prescribing Information including Dosage
Avinza - User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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