Axert (Almotriptan Malate) Drug Overview and Uses for Patients and Caregivers at RxList

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May 25, 2012

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Migraine »

What is a migraine headache?

A migraine headache is a form of vascular headache. Migraine headache is caused by vasodilatation (enlargement of blood vessels) that causes the release of chemicals from nerve fibers that coil around the large arteries of the brain. Enlargement of these blood vessels stretches the nerves that coil around them and causes the nerves to release chemicals. The chemicals cause inflammation, pain, and further enlargement of the artery. The increasing enlargement of the arteries magnifies the pain.

Migraine attacks commonly activate the sympathetic nervous system in the body. The sympathetic nervous system is often thought of as the part of the nervous system that controls primitive responses to stress and pain, the so-called "fight or flight" response, and this activation causes many of the symptoms associated with migraine attacks; for example, the increased sympathetic nervous activity in the intestine causes nausea, vomiting,...

Read the Migraine article »

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Axert Consumer

IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

ALMOTRIPTAN - ORAL

(AL-moe-TRIP-tan)

COMMON BRAND NAME(S): Axert

USES: Almotriptan is used to treat migraines. It helps to relieve headaches, pain and other symptoms of migraines, including sensitivity to light/sound, nausea, and vomiting. Prompt treatment allows you to get back to your normal routine and may decrease your need for other pain medications. Almotriptan does not prevent future migraines or reduce how often you may get a headache.

Almotriptan belongs to a group of drugs called triptans. It affects a certain natural chemical (serotonin) that constricts blood vessels in the brain. It may also block other pain pathways in the brain.

HOW TO USE: Read the Patient Information Leaflet available from your pharmacist before you start using almotriptan and each time you get a refill. Ask your doctor or pharmacist if you have any questions.

Take this medication by mouth at the first sign of a migraine, or as directed by your doctor. It may be taken with or without food. Do not take almotriptan to prevent a migraine. If there is no improvement in your symptoms, do not take any more doses of this medication before talking to your doctor.

If your symptoms are only partly relieved, or if your headache comes back, you may take a second dose after 2 hours or as directed by your doctor. Do not take more than 2 doses in a 24-hour period.

If you have never taken this medication before and you have risk factors for heart disease (see Precautions), you may be advised to take your first dose in your doctor's office in order to monitor for rare but serious heart problems (e.g., heart attack).

Your dosage is based on your medical condition and response to therapy. Tell your doctor if your condition does not improve or if it worsens.