Axid Oral Solution
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Axid Oral Solution
Adverse Reactions (Pediatric)
In controlled clinical trials in pediatric patients (age 2 to 18 years), nizatidine was found to be generally safe and well tolerated. The principal adverse experiences (> 5%) were pyrexia, nasopharyngitis, diarrhea, vomiting, irritability, nasal congestion and cough. Most adverse events were mild or moderate in severity. Mild elevations in serum transaminase (1-2 x ULN) were noted in some patients. One subject experienced a seizure by EEG diagnosis after taking Axid® Oral Solution 2.5 mg/kg BID for 23 days. The adverse reactions reported for nizatidine may also occur with Axid® Oral Solution.
Read the Axid Oral Solution (nizatidine) Side Effects Center for a complete guide to possible side effects
No interactions have been observed between nizatidine and theophylline, chlordiazepoxide, lorazepam, lidocaine, phenytoin, and warfarin. Nizatidine does not inhibit the cytochrome P-450-linked drug-metabolizing enzyme system; therefore, drug interactions mediated by inhibition of hepatic metabolism are not expected to occur. In patients given very high doses (3,900 mg) of aspirin daily, increases in serum salicylate levels were seen when nizatidine, 150 mg b.i.d., was administered concurrently.
Read the Axid Oral Solution Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 8/24/2012
This monograph has been modified to include the generic and brand name in many instances.
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