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Azactam Injection

E. coli 0157:H7 Facts

  • E. coli 0157:H7 is a gram-negative bacterium that can produce a bloody diarrhea due to toxins it secretes when it infects human intestinal tracts.
  • The symptoms of E. coli 0157:H7 infection may include a low fever, nausea, vomiting, stomach cramps, and bloody diarrhea.
  • E. coli 0157:H7 is notorious because it can cause additional complications in children and the elderly; renal failure, anemia, and dehydration especially for children (termed HUS or Hemolytic-uremic syndrome) and spontaneous bleeding, organ failures, and mental changes in the elderly (termed TTP or thrombotic thrombocytopenic purpura). Some of these patients develop disabilities or die.
  • Diagnosis is definitively made when E. coli 0157:H7 is isolated, usually from the patient's stool, and identified as serotype 0157 by immunologic tests.
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Azactam Injection

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OVERDOSE

If necessary, aztreonam may be cleared from the serum by hemodialysis and/or peritoneal dialysis.

CONTRAINDICATIONS

This preparation is contraindicated in patients with known hypersensitivity to aztreonam or any other component in the formulation.

Last reviewed on RxList: 8/28/2009
This monograph has been modified to include the generic and brand name in many instances.

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