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Azactam Injection

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Azactam Injection

Azactam Injection Patient Information including How Should I Take

What should I discuss with my health care provider before using aztreonam (Azactam Injection)?

You should not use this medication if you are allergic to aztreonam or to a penicillin antibiotic, such as:

  • amoxicillin (Amoxil, Augmentin, Amoxicot, Biomox, Dispermox, Trimox);
  • ampicillin (Omnipen, Principen);
  • carbenicillin (Geocillin);
  • dicloxacillin (Dycill, Dynapen);
  • oxacillin (Bactocill); or
  • penicillin (Beepen-VK, Ledercillin VK, Pen-V, Pen-Vee K, Pfizerpen, V-Cillin K, Veetids, and others).

Also tell your doctor if you are allergic to any other drugs, especially:

  • cephalosporins such as cefdinir (Omnicef), cefprozil (Cefzil), cefuroxime (Ceftin), cephalexin (Keflex), and others; or
  • similar antibiotics such as ertapenem (Invanz), imipenem (Primaxin), or meropenem (Merrem).

If you have any of these other conditions, you may need an aztreonam dose adjustment or special tests:

  • liver disease;
  • kidney disease; or
  • a history of any type of allergy.

FDA pregnancy category B. Aztreonam is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Aztreonam can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use aztreonam (Azactam Injection)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Aztreonam is injected into a muscle or a vein. Aztreonam is usually given in a clinic or hospital setting. The medicine may need to be given for several hours or several weeks, depending on how severe your infection is.

You may be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

Aztreonam is usually given as long as needed until your infection has cleared or you have been symptom-free for at least 48 hours.

Use aztreonam for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Aztreonam will not treat a viral infection such as the common cold or flu.

Do not give this medication to another person, even if they have the same symptoms you have.

Aztreonam is supplied as a frozen solution in a plastic container. If you use this medicine at home, store the frozen medicine in a freezer. If possible, keep the freezer set at 4 degrees below 0 Fahrenheit or colder.

Thaw the medicine either in a refrigerator or at room temperature. Do not heat the medicine to thaw it more quickly. Aztreonam that is thawed in the refrigerator should be used within 2 weeks.

If you have thawed the medicine at room temperature, you must use it within 48 hours.

Once aztreonam has been thawed, it should be clear and appear colorless or slightly yellow. Do not use the medicine if it has changed color or has particles in it, or if the medicine container leaks. Call your doctor or pharmacist for a new prescription.

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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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