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Azasite

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Azasite

AzaSite®
(azithromycin) Ophthalmic Solution

Azasite

DRUG DESCRIPTION

AzaSite (azithromycin ophthalmic solution) is a 1% sterile aqueous topical ophthalmic solution of azithromycin formulated in DuraSite® (polycarbophil, edetate disodium, sodium chloride). AzaSite is an off-white, viscous liquid with an osmolality of approximately 290 mOsm/kg.

Preservative: 0.003% benzalkonium chloride. Inactives: mannitol, citric acid, sodium citrate, poloxamer 407, polycarbophil, edetate disodium (EDTA), sodium chloride, water for injection, and sodium hydroxide to adjust pH to 6.3.

Azithromycin is a macrolide antibiotic with a 15-membered ring. Its chemical name is (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribohexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6trideoxy-3-(dimethylamino)-&beata;-D-xylo-hexopyranosyl]oxy]-1-oxa-6-aza-cyclopentadecan-15one, and the structural formula is:

AzaSite® (azithromycin) Structural Formula Illustration

Azithromycin has a molecular weight of 749, and its empirical formula is C38H72N2O12.

What are the possible side effects of azithromycin ophthalmic (AzaSite)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when azithromycin ophthalmic is used in the eyes, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream. Stop using the medicine and get emergency medical help if you have any signs of a severe skin reaction, such as:

  • fever, sore throat;
  • swelling in your face or tongue, burning in your...

Read All Potential Side Effects and See Pictures of Azasite »

What are the precautions when taking azithromycin ophthalmic solution (Azasite)?

Before using azithromycin, tell your doctor or pharmacist if you are allergic to it; or to other macrolide antibiotics such as erythromycin or clarithromycin; or to ketolide antibiotics such as telithromycin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other eye problems.

After you apply this drug, your vision may become temporarily blurred. Do not drive, use machinery, or do any activity that requires clear vision until you are sure you can perform such activities safely.

During pregnancy, this medication should be used only when...

Read All Potential Precautions of Azasite »

Last reviewed on RxList: 9/4/2012
This monograph has been modified to include the generic and brand name in many instances.

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Azasite - User Reviews

Azasite User Reviews

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Here is a collection of user reviews for the medication Azasite sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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