"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.
Patients should be told:
- To use AZELEX (azelaic acid cream) Cream for the full prescribed treatment period.
- To avoid the use of occlusive dressings or wrappings.
- To keep AZELEX (azelaic acid cream) Cream away from the mouth, eyes and other mucous membranes. If it does come in contact with the eyes, they should wash their eyes with large amounts of water and consult a physician if eye irritation persists.
- If they have dark complexions, to report abnormal changes in skin color to their physician.
- Due in part to the low pH of azelaic acid, temporary skin irritation (pruritus, burning, or stinging) may occur when AZELEX (azelaic acid cream) Cream is applied to broken or inflamed skin, usually at the start of treatment. However, this irritation commonly subsides if treatment is continued. If it continues, AZELEX (azelaic acid cream) Cream should be applied only once-a-day, or the treatment should be stopped until these effects have subsided. If troublesome irritation persists, use should be discontinued, and patients should consult their physician. (See ADVERSE REACTIONS.)
Last reviewed on RxList: 11/11/2008
This monograph has been modified to include the generic and brand name in many instances.
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