Azilect (Rasagiline) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Azilect

Parkinson's Disease: Eating Right »

Introduction to eating right with Parkinson's disease

While there is no special diet required for people with Parkinson's disease, eating a well-balanced, nutritious diet is extremely beneficial. With the proper diet, our bodies work more efficiently, we have more energy, and Parkinson's disease medications will work properly.

This article addresses the basics of good nutrition. Please consult your doctor or dietitian before making any dietary changes. A registered dietitian can provide in-depth nutrition education, tailor these general guidelines to meet your needs, and help you create and follow a personal meal plan.

The Basics of Eating Well

Eat a variety of foods from each food category. Ask your doctor if you should take a daily vitamin supplement.
Maintain your weight through a proper balance of exercise and food. Ask your doctor what your "goal" weight should be and how many calories you should consume ...

Read the Parkinson's Disease: Eating Right article »

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AZILECT®
(rasagiline mesylate) Tablets for Oral Use

DRUG DESCRIPTION

AZILECT® tablets contain rasagiline (as the mesylate), a propargylamine-based d rug indicated for the treatment of idiopathic Parkinson's disease. It is designated chemically as: 1H-Inden-1-amine, 2, 3dihydro-N-2-propynyl-, (1R)-, methanesulfonate. The empirical formula of rasagiline mesylate is (C₁₂H₁₃N)CH₄SO₃ and its molecular weight is 267.34. Its structural formula is:

AZILECT® (rasagiline mesylate) Structural Formula Illustration

Rasagiline mesylate is a white to off-white powder, freely soluble in water or ethanol and sparingly soluble in isopropanol. Each AZILECT tablet for oral administration contains rasagiline mesylate equivalent to 0.5 mg or 1 mg of rasagiline base.

Each AZILECT (rasagiline) tablet also contains the following inactive ingredients: mannitol, starch, pregelatinized starch, colloidal silicon dioxide, stearic acid and talc.

What are the possible side effects of rasagiline (Azilect)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using rasagiline and call your doctor at once if you have any of these serious side effects:

increased blood pressure (sudden and severe headache, confusion, blurred vision, chest pain, nausea, vomiting, seizure);
sudden numbness or weakness (especially on one side of the body), problems with speech or balance;
unusual thoughts or behavior,...

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What are the precautions when taking rasagiline (Azilect)?

Before taking rasagiline, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: cerebrovascular disease (e.g., stroke), heart disease (e.g., coronary artery disease, heart attack, history of chest pain, congestive heart failure), personal/family history of high blood pressure, history of severe/frequent headaches, liver disease, sore in the stomach/intestine/esophagus (peptic ulcer), bleeding problems, diabetes, personal/family history of mental/mood disorders (e.g., schizophrenia, bipolar disorder),...

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Last reviewed on RxList: 12/29/2009
This monograph has been modified to include the generic and brand name in many instances.