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Brand Names: Azor

Generic Name: amlodipine and olmesartan (Pronunciation: am LOE de peen ol me SAR tan)

• What is amlodipine and olmesartan (Azor)?
• What are the possible side effects of amlodipine and olmesartan (Azor)?
• What is the most important information I should know about amlodipine and olmesartan (Azor)?
• What should I discuss with my healthcare provider before taking amlodipine and olmesartan (Azor)?
• How should I take amlodipine and olmesartan (Azor)?
• What happens if I miss a dose (Azor)?
• What happens if I overdose (Azor)?
• What should I avoid while taking amlodipine and olmesartan (Azor)?
• What other drugs will affect amlodipine and olmesartan (Azor)?
• Where can I get more information?

What is amlodipine and olmesartan (Azor)?

Amlodipine is in a group of drugs called calcium channel blockers. It works by relaxing the muscles of your heart and blood vessels.

Olmesartan is in a group of drugs called angiotensin II receptor antagonists. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

The combination of amlodipine and olmesartan is used to treat high blood pressure (hypertension).

Amlodipine and olmesartan may also be used for other purposes not listed in this medication guide.

What are the possible side effects of amlodipine and olmesartan (Azor)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, amlodipine and olmesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.

Call your doctor at once if you have any other serious side effects, such as:

• feeling like you might pass out;
• swelling in your hands or feet, rapid weight gain;
• fast or pounding heartbeats;
• urinating less than usual or not at all;
• jaundice (yellowing of the skin or eyes); or
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.

Less serious side effects include:

• dizziness, drowsiness;
• warmth, redness, or tingly feeling under your skin;
• hair loss; or
• mild skin rash or itching.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about amlodipine and olmesartan (Azor)?

Do not use this medication without telling your doctor if you are pregnant. Olmesartan may cause injury and even death to the unborn baby if you take it during the second and third trimesters of pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Do not use potassium supplements or salt substitutes while you are taking amlodipine and olmesartan, unless your doctor has told you to.

Call your doctor at once if you have swelling in your hands or feet, rapid weight gain, fast or pounding heartbeats, jaundice (yellowing of the skin or eyes), chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, or if you feel like you might pass out.

In rare cases, amlodipine and olmesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.