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Virtually any disease as well as most injuries and surgical procedures involve some degree of pain. It's not surprising, then, that pain medications, also known as analgesics, are among the most commonly used drugs in the U.S. Pain can range from minor, acute complaints, such as a muscle sprain, to chronic, severe pain, such as that sometimes experienced by cancer patients. Some drugs used for other conditions also are effective at relieving certain types of pain. These drugs include certain drugs used for depression, epilepsy, and anxiety.
Pain medications can be broadly classified into two categories: prescription and nonprescription. In the latter category are several mild anti-inflammatory drugs (ibuprofen, naproxen), as well as acetaminophen. These are mainly meant for use with short-term, acute pain -- menstrual cramps,...
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Pharmacy Author: Omudhome Ogbru, PharmD
Medical Editor: Melissa Conrad Stöppler, MD
Baclofen is a muscle relaxant used for treating spasm of skeletal muscles, muscle clonus, rigidity, and pain caused by multiple sclerosis. It is also injected into the spinal cord to treat severe spasticity, spinal cord injuries, and other spinal cord diseases. A generic version is available. Baclofen side effects include drowsiness, weakness, dizziness, headache, seizures, nausea, vomiting, low blood pressure, constipation, confusion, respiratory depression, insomnia, and increased urinary frequency or urinary retention. Abrupt discontinuation of baclofen may cause seizures and hallucinations, high fever, rebound spasticity, muscle rigidity, and rhabdomyolysis. The recommended oral dose of baclofen is 15-80 mg daily. Combining baclofen and tricyclic antidepressants may cause muscle weakness. Use of baclofen and monoamine oxidase inhibitors (MAOIs) can result in greater depression of brain function as well as low blood pressure. The use of baclofen by pregnant women has not been evaluated. Baclofen can be detected in the breast milk when administered orally. Our Baclofen Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions.
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Baclofen (baclofen (baclofen (baclofen tablets) tablets) tablets) is useful for the alleviation of signs and symptoms of spasticity resulting from multiple sclerosis, particularly for the relief of flexor spasms and concomitant pain, clonus, and muscular rigidity.
Patients should have reversible spasticity so that baclofen (baclofen (baclofen (baclofen tablets) tablets) tablets) treatment will aid in restoring residual function.
Baclofen (baclofen (baclofen (baclofen tablets) tablets) tablets) may also be of some value in patients with spinal cord injuri...
Read the complete drug monograph for Baclofen »
Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More
What is Consumer information?
A concise overview of the drug for the patient or caregiver from First DataBank.
HOW TO USE: Take this medication by mouth, usually 3 times a day or as directed by your doctor. In general, your doctor may slowly increase your dose to lower your chance of side effects until the right dose for you is determined. ...
Read the complete consumer information for Baclofen »
Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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