November 26, 2015
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"The European Medicines Agency (EMA) today issued updated recommendations on ways to minimize the risk for progressive multifocal leukoencephalopathy with dimethyl fumarate (Tecfidera, Biogen).

To date, three cases of PML have"...




Signs and symptoms: Vomiting, muscular hypotonia, drowsiness, accommodation disorders, coma, respiratory depression, and seizures.

Treatment: In the alert patient, empty the stomach promptly by induced emesis followed by lavage. In the obtunded patient, secure the airway with a cuffed endotracheal tube before beginning lavage (do not induce emesis). Maintain adequate respiratory exchange, do not use respiratory stimulants.


Hypersensitivity to baclofen (baclofen (baclofen (baclofen tablets) tablets) tablets) .

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 11/20/2007


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