Bactroban Nasal (Mupirocin Calcium Ointment) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 25, 2012

Bactroban Nasal

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Common, noninfectious rashes are listed below. Since these conditions are not caused by infectious organisms, it is reasonable to attempt to treat them with over-the-counter 1% hydrocortisone cream for a week or so prior to seeking medical attention.

Seborrheic dermatitis: Seborrheic dermatitis is the single most common rash affecting adults. It produces a red, scaling eruption that characteristically affects the scalp, forehead, brows, cheeks, and external ears.

Atopic dermatitis: Atopic dermatitis, often called eczema, is a common disorder of childhood which produces red, itchy, weeping rashes on the inner aspects of the elbows and in back of the knees as well as the cheeks, neck, wrists, and ankles. It is commonly found in patients who also have asthma and hay fever.

Contact dermatitis: Contact dermatitis is a rash that i...

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Bactroban Nasal

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BACTROBAN NASAL®
(mupirocin calcium) Ointment, 2%

for intranasal use only

DRUG DESCRIPTION

BACTROBAN NASAL (mupirocin calcium ointment, 2%) contains the dihydrate crystalline calcium hemi-salt of the antibiotic mupirocin. Chemically, it is (αE,2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid, calcium salt (2:1), dihydrate.

The molecular formula of mupirocin calcium is (C₂₆H₄₃O₉)₂Ca•2H₂O, and the molecular weight is 1075.3. The molecular weight of mupirocin free acid is 500.6. The structural formula of mupirocin calcium is:

BACTROBAN NASAL®
(mupirocin calcium ointment, 2%) Structural Formula Illustration

BACTROBAN NASAL (mupirocin calcium ointment) is a white to off-white ointment that contains 2.15% w/w mupirocin calcium (equivalent to 2.0% pure mupirocin free acid) in a soft white ointment base. The inactive ingredients are paraffin and a mixture of glycerin esters (SOFTISAN® 649).

What are the possible side effects of mupirocin nasal (Bactroban)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using mupirocin nasal and call your doctor at once if you have any of these serious side effects:

severe burning or stinging of your nose;
nosebleed; or
severe burning or watering of your eyes.

Less serious side effects may include:

dryness or unpleasant taste in your mouth;
headache;

Read All Potential Side Effects and See Pictures of Bactroban Nasal »

What are the precautions when taking mupirocin calcium ointment (Bactroban Nasal)?

Before taking mupirocin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history.

This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.

It is not known whether this drug passes into breast milk. Consult your doctor before...

Read All Potential Precautions of Bactroban Nasal »

Last reviewed on RxList: 12/9/2008
This monograph has been modified to include the generic and brand name in many instances.