September 4, 2015

Baikal Skullcap

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Are there any interactions with medications?



Alcohol
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Alcohol can cause sleepiness and drowsiness. Baikal skullcap might also cause sleepiness and drowsiness. Taking large amounts of Baikal skullcap along with alcohol might cause too much sleepiness.



Estrogens
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might have some of the same effects as estrogen. However Baikal skullcap is not as strong as estrogen pills. Taking Baikal skullcap along with estrogen pills might decrease the effects of estrogen pills.

Some estrogen pills include conjugated equine estrogens (Premarin), ethinyl estradiol, estradiol, and others.



Lithium
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might have an effect like a water pill or "diuretic." Taking Baikal skullcap might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects. Talk with your healthcare provider before using this product if you are taking lithium. Your lithium dose might need to be changed.



Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Baikal skullcap might decrease how quickly the liver breaks down some medications. Taking Baikal skullcap along with some medications that are changed by the liver might increase the effects and side effects of some medications. Before taking Baikal skullcap, talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.



Medications changed by the liver (Cytochrome P450 2C19 (CYP2C19) substrates)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Some medications are changed and broken down by the liver. Baikal skullcap might increase how quickly the liver breaks down some medications. Taking Baikal skullcap with these medications might decrease how well the medication works. Before taking Baikal skullcap, talk to your healthcare provider if you take any medications that are changed by the liver.

Some of these medications that are changed by the liver include amitriptyline (Elavil), carisoprodol (Soma), citalopram (Celexa), diazepam (Valium), lansoprazole (Prevacid), omeprazole (Prilosec), phenytoin (Dilantin), warfarin (Coumadin), and many others.



Medications for diabetes (Antidiabetes drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might decrease blood sugar. Diabetes medications are also used to lower blood sugar. Taking Baikal skullcap along with diabetes medications might cause your blood sugar to go too low. Monitor your blood sugar closely. The dose of your diabetes medication might need to be changed.

Some medications used for diabetes include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.



Medications for high blood pressure (Antihypertensive drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might lower blood pressure. Taking Baikal skullcap with medications used to treat high blood pressure might cause blood pressure levels to go to low.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), amlodipine (Norvasc), hydrochlorothiazide (HydroDIURIL), furosemide (Lasix), and many others.



Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might slow blood clotting. Taking Baikal skullcap along with medications that also slow clotting might increase the chances of bruising and bleeding.

Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, indomethacin (Indocin), ticlopidine (Ticlid), warfarin (Coumadin), and others.



Metformin (Glucophage)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Metformin (Glucophage) is used to help decrease blood sugar. Baikal skullcap might also lower blood sugar. Taking Baikal skullcap along with metformin (Glucophage) might increase the effectiveness of metformin (Glucophage) for lowering blood sugar. Monitor your blood sugar closely. The dose of your metformin (Glucophage) might need to be changed.



Sedative medications (Benzodiazepines)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might cause sleepiness and drowsiness. Medications that cause sleepiness and drowsiness are called sedatives. Taking Baikal skullcap along with sedative medications might cause too much sleepiness.

Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.



Sedative medications (CNS depressants)
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking Baikal skullcap along with sedative medications might cause too much sleepiness.

Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.



Medications moved by pumps in cells (P-glycoprotein Substrates)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Some medications are moved by pumps into cells. Baikal skullcap might make these pumps less active and increase how much of some medications get absorbed by the body. This might increase the side effects of some medications.

Some medications that are moved by these pumps include etoposide, paclitaxel, vinblastine, vincristine, vindesine, ketoconazole, itraconazole, amprenavir, indinavir, nelfinavir, saquinavir, cimetidine, ranitidine, diltiazem, verapamil, corticosteroids, erythromycin, cisapride (Propulsid), fexofenadine (Allegra), cyclosporine, loperamide (Imodium), quinidine, and others.



Medications used for lowering cholesterol (Statins)
Interaction Rating: Minor Be cautious with this combination.
Talk with your health provider.

Baikal skullcap might change the levels of statins in your blood. But there isn't enough information to know if this is an important interaction. Talk with your healthcare provider before using Baikal skullcap if you are taking medications used for lowering cholesterol.

These medications include atorvastatin (Lipitor), cerivastatin (Baycol), fluvastatin (Lescol), lovastatin (Mevacor), pravastatin (Pravachol), and simvastatin (Zocor).

Dosing considerations for Baikal Skullcap.

The appropriate dose of Baikal skullcap depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for Baikal skullcap. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

Therapeutic Research Faculty copyright

Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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