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Local pain and tenderness at the injection site, urticaria, and angioedema may occur. Anaphylactic reactions, although rare, have been reported following the injection of human immune globulin preparations.6,9 Anaphylaxis is more likely to occur if BayGam (immune globulin) is given intravenously; therefore, BayGam (immune globulin) must be administered only intramuscularly.
Antibodies in the globulin preparation may interfere with the response to live viral vaccines such as measles, mumps, polio and rubella. Therefore, use of such vaccines should be deferred until approximately 3 months after Immune Globulin (Human) — BayGam™ (immune globulin) administration.
No interactions with other products are known.
REFERENCE
6. American Academy of Pediatrics, Committee on Infectious Diseases: Report. ed. 19. Evanston, 1982, pp 134-5.
9. Fudenberg HH: Sensitization to immunoglobulins and hazards of gamma globulin therapy. In: Merler E (ed.): Immunoglobulins: biologic aspects and clinical uses. Washington DC, Nat Acad Sci, 1970, pp 211-20.
Last reviewed on RxList: 11/13/2008
This monograph has been modified to include the generic and brand name in many instances.
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