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Belladonna and Opium

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Belladonna and Opium

atropa belladonna and opium suppository


Each belladonna and opium suppository contains (in a water-soluble base consisting of Polyethylene Glycol 400, 1450, 8000 and Polysorbate 60):

Belladonna (16.2 mg) And Opium (30 mg)

Powdered opium 30 mg (Warning: May be habit forming.) and powdered belladonna extract 16.2 mg.

Belladonna (16.2 mg) And Opium (60 mg)

Powdered opium 60 mg (Warning: May be habit forming.) and powdered belladonna extract 16.2 mg.

This drug falls into the pharmacological/therapeutic class of narcotic analgesic/antispasmotic agents.

The pharmacologically active principles present in the belladonna extract component of belladonna and opium suppositories are:

Atropine - Structural Formula Illustration 1

Established Name: Atropine
Chemical Name: dl Tropyl Tropate

Scopolamine - Structural Formula Illustration 2

Established Name: Scopolamine
Chemical Name: dl Scopolamine

Opium contains more than twenty alkaloids, the principle ones being morphine (10%), narcotine (6%), papaverine (1%) and codeine (0.5%). The major pharmacologically active principle of the powdered opium component of belladonna and opium suppositories, however, is:

Morphine - Structural Formula Illustration 3

Name: Morphine
Chemical Name: 7, 8-Didehydro-4, 5-epoxy- 17-Methyl-morphinan-3, 6-diol

What are the possible side effects of belladonna and opium (B & O Supprettes 15-A, B & O Supprettes 16-A)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • painful or difficult urination;
  • urinating less than usual or not at all;
  • fast heart rate;
  • weak, shallow breathing;
  • extreme weakness, feeling like you might pass out;
  • headache, confusion; or
  • severe constipation and stomach pain.


Read All Potential Side Effects and See Pictures of Belladonna and Opium »

What are the precautions when taking belladonna and opium (Belladonna and Opium)?

Before using this product, tell your doctor or pharmacist if you are allergic to belladonna or opium; or to narcotic pain medications (such as morphine, codeine); or to atropine or scopolamine; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: a certain muscle/nerve disease (myasthenia gravis), certain stomach/bowel diseases (paralytic ileus, blockage, infectious diarrhea), glaucoma (narrow-angle).

Before using this medication, tell your doctor or pharmacist your medical history, especially of:...

Read All Potential Precautions of Belladonna and Opium »

Last reviewed on RxList: 8/8/2016
This monograph has been modified to include the generic and brand name in many instances.

Belladonna and Opium - User Reviews

Belladonna and Opium User Reviews

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Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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