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In this Article

• What is belladonna and opium (Belladonna and Opium)?
• What are the possible side effects of belladonna and opium (Belladonna and Opium)?
• What is the most important information I should know about belladonna and opium (Belladonna and Opium)?
• What should I discuss with my health care provider before using belladonna and opium rectal (Belladonna and Opium)?
• How should I use belladonna and opium rectal (Belladonna and Opium)?
• What happens if I miss a dose (Belladonna and Opium)?
• What happens if I overdose (Belladonna and Opium)?
• What should I avoid while using belladonna and opium (Belladonna and Opium)?
• What other drugs will affect belladonna and opium (Belladonna and Opium)?
• Where can I get more information?

What should I discuss with my health care provider before using belladonna and opium rectal (Belladonna and Opium)?

Do not use belladonna and opium if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you use belladonna and opium before the MAO inhibitor has cleared from your body.

Do not use belladonna and opium if you are also using furazolidone (Furoxone), linezolid (Zyvox), moclobemide, pramlintide (Symlin), procarbazine (Matulane), naltrexone (ReVia), or potassium supplement tablets or capsules.

You should not use this medication if you are allergic to belladonna or opium, or if you have:

• glaucoma;
• urination problems or an enlarged prostate;
• severe kidney disease;
• a blockage in your stomach or intestines;
• a history of head injury or brain tumor;
• epilepsy or other seizure disorder;
• an infection causing diarrhea;
• severe liver disease;
• severe bleeding;
• a muscle disorder such as myasthenia gravis;
• asthma or severe breathing disorder;
• if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications; or
• if you are bed-ridden or otherwise debilitated.

If you have certain conditions, you may need a dose adjustment or special tests to safely use belladonna and opium. Before using, tell your doctor if you have:

• liver or kidney disease;
• heart disease, high or low blood pressure;
• a stomach or intestinal disorder;
• chronic obstructive pulmonary disease (COPD) or other breathing problems;
• depression or mental illness;
• curvature of the spine;
• gallbladder disease;
• Addison's disease or other adrenal gland disorders;
• underactive thyroid;
• drug or alcohol addiction; or
• an allergy to atropine or any narcotic pain medicine such as hydrocodone (Lortab, Vicodin), morphine (Kadian, MS Contin, Oramorph, and others), oxycodone (OxyContin), and others.

FDA pregnancy category C. Belladonna and opium may be harmful to an unborn baby. It could also cause addiction or withdrawal symptoms in a newborn if the mother uses the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Belladonna and opium can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Opium may be habit-forming and should be used only by the person it was prescribed for. Belladonna and opium rectal suppositories should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

Older adults may be more sensitive to the effects of this medicine.

How should I use belladonna and opium rectal (Belladonna and Opium)?

Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Do not take belladonna and opium rectal by mouth. It is for use only in your rectum.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Wash your hands before and after inserting the rectal suppository.

Try to empty your bowel and bladder just before using the belladonna and opium suppository. Use this medicine at a time when you can lie down afterward and hold the medicine in for a few minutes.

Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands. Moisten the suppository with water to make it easier to insert.

Lie on your back with your knees up toward your chest. Gently insert the suppository into your rectum about 1 inch.

For best results, stay lying down after inserting the suppository and hold it in your rectum for a few minutes. The suppository will melt quickly once inserted and you should feel little or no discomfort while holding it in. Avoid using the bathroom for at least an hour after using the suppository.

Drink plenty of water to prevent constipation while using belladonna and opium.

Belladonna and opium rectal is most often used 1 or 2 times per day. Do not use the suppositories more than 4 times per day. Follow your doctor's instructions. Call your doctor if your symptoms do not improve, or if they get worse while using this medication.

Do not stop using the medication suddenly after long-term use, or you could have unpleasant withdrawal symptoms. Talk to your doctor about how to avoid withdrawal symptoms when you stop using belladonna and opium rectal.

Store the rectal suppositories at room temperature away from moisture, heat, and light. Do not refrigerate or freeze this medication.

Ask your pharmacist how to properly dispose of any unused suppositories that are no longer needed.

Keep track of how many suppositories have been used from each new bottle of this medicine. Opium is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.