March 25, 2017
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Belviq XR

"Low body mass index (BMI) and high body fat percentage, not just high BMI, are independently associated with increased mortality in both men and women, a new study suggests.

Raj Padwal, MD, from the University of Alberta, Edmonton, Ca"...

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Belviq XR

BELVIQ XR®
(lorcaserin hydrochloride) Extended-release Tablets

DRUG DESCRIPTION

BELVIQ XR (lorcaserin hydrochloride) extended-release tablets for oral use is a serotonin 2C receptor agonist for oral administration used for chronic weight management. Its chemical name is (R)-8-chloro-1-methyl2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate. The empirical formula is C11H15Cl2N·0.5H2O, and the molecular weight of the hemihydrate form is 241.16 g/mol.

The structural formula is:

BELVIQ XR® (lorcaserin hydrochloride) Structural Formula Illustration

Lorcaserin hydrochloride hemihydrate is a white to off-white powder with solubility in water greater than 400 mg/mL. Each BELVIQ XR tablet contains 20.8 mg of crystalline lorcaserin hydrochloride hemihydrate, equivalent to 20.0 mg anhydrous lorcaserin hydrochloride, and the following inactive ingredients: microcrystalline cellulose NF; mannitol USP; hypromellose 2208 USP; ethylcellulose dispersion Type B NF; hypromellose 2910 USP; colloidal silicon dioxide NF; polyvinyl alcohol USP; polyethylene glycol NF; titanium dioxide USP; talc USP; FD&C yellow #6/sunset yellow FCF; aluminum lake; iron oxide yellow NF; iron oxide red NF; and magnesium stearate NF.

Last reviewed on RxList: 7/27/2016
This monograph has been modified to include the generic and brand name in many instances.

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