Benadryl Injection (Diphenhydramine Injection) Drug Information: Clinical Pharmacology

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May 25, 2012

Benadryl Injection

Scabies »

Scabies facts

Scabies is an itchy, highly contagious skin condition caused by an infestation by the itch mite Sarcoptes scabiei.
Direct skin-to-skin contact is the mode of transmission.
A severe and relentless itch is the predominant symptom of scabies.
Sexual contact is the most common form of transmission among sexually active young people, and scabies has been considered by many to be a sexually transmitted disease (STD).
Scabies produces a skin rash composed of small red bumps and blisters and affects specific areas of the body.
Treatment includes oral or topical scabicidal drugs.

What is scabies?

Scabies is an itchy, highly contagious skin disease caused by an infestation by the itch mite Sarcoptes scabiei. Mites are small eight-legged parasites (in contrast to insects, which have six legs). They are tiny, just 1/3 millimeter long, and burrow into the sk...

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CLINICAL PHARMACOLOGY

Diphenhydramine hydrochloride is an antihistamine with anticholinergic (drying) and sedative side effects. Antihistamines appear to compete with histamine for cell receptor sites on effector cells.

Benadryl in the injectable form has a rapid onset of action. Diphenhydramine hydrochloride is widely distributed throughout the body, including the CNS. A portion of the drug is excreted unchanged in the urine, while the rest is metabolized via the liver. Detailed information on the pharmacokinetics of Diphenhydramine Hydrochloride Injection is not available.

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.